(Updated 7/17/20). Have you heard of the anti-aging supplement Protandim? Maybe you saw a YouTube video of when Protandim was featured on ABC's PrimeTime? Protandim called an “Nrf2 activator” has been said to be the “only supplement clinically proven to reduce oxidative stress in humans by an average of 40 percent in 30 days.” That’s fancy talk for Protandim is a type of antioxidant supplement. Unlike other products, Protandim is said to work by helping the body increase its own natural antioxidant enzymes. Sounds good, but does Protandim work, or is it a scam? These are some of the questions I will address in this review. The good news is there are clinical studies on Protandim. I will use that research in this review and help you understand it. By the end of this review, you'll have a better idea if Protandim is right for you.
Other Anti-Aging Supplement Reviews
What Is Protandim?
Protandim might sound like a drug but it's really a dietary supplement. It's said to combat free radical damage (oxidative stress) by stimulating the production of the body's own natural antioxidant enzymes such as catalase, superoxide dismutase (SOD), and glutathione.
The idea goes like this: instead of taking individual antioxidant supplements (like vitamins C, E, etc.) in the hopes they will battle free radicals and combat aging and disease, Protandim is supposed to augment or ramp up your own naturally occurring free radical defenses.
It's a novel concept to be sure.
The supplement website (LifeVantage.com) says the supplement is “clinically proven to reduce oxidative stress to levels of that of a 20-year-old.” Oxidative stress refers to the stress (cellular damage) caused by free radicals.
What Does The Name Mean?
My guess is the name was chosen because the ingredients are supposed to “pro-actively” work in “tandim” to help defend us against aging and disease.
Who Makes Protandim?
Protandim is a product of a company called LifeVantage Corporation. LifeVantage is actually a publicly traded stock on the NASDAQ. Its stock symbol is LFVN.
The company is located at 9785 S. Monroe Street, Suite 300 Sandy, UT 84070. If you google this address you will see a building with “LifeVantage” at the top. That is good. It tells us the company has a physical location.
Contact LifeVantage
Call the company at 866-460-7241.
The Better Business Bureau gave LifeVantage an A- rating when this review was updated. See the BBB file for updates and more information.
Protandim Ingredients
According to the product's website, there are 5 ingredients in each caplet of Protandim which add up to 625 mg:
| Amount Per Serving (1 caplet) | Percent Daily Value |
|---|---|
| Calcium (as dicalcum phosphate & calcium carbonate) 77 mg | 8% DV |
| Proprietary Blend Consisting of the following | 675 mg |
| Milk thistle extract (Silybum marianum) seed. | |
| Bacopa extract (Bacopa monnieri) whole herb | |
| Ashwagandha extract (Withania somnifera) root | |
| Green tea extract (Camellia sinensis) leaf | |
| Turmeric extract (Curcuma longa) rhizome |
Notice in the table above they tell us the source of each ingredient:
- The milk thistle extract is derived from the seeds of the plant
- The bacopa extract is derived from the whole plant
- The ashwagandha extract is derived from the root of the plant
- The green tea extract comes from the leaves of the plant
- The turmeric extract is derived from the underground stems (rhizome) of the plant
Other Ingredients
The supplement label also tells the supplement has these other ingredients:
- Microcrystalline Cellulose
- Croscarmellose Sodium Silica
- Modified Cellulose
- Stearic Acid
- Magnesium Stearate
- Maltodextrin
- Medium Chain Triglycerides
These other ingredients play no role in the effects or benefits of the product. They make up the caplets and/or help with the delivery of the ingredients into the body.
I want to commend the LifeVantage company for sponsoring much of the research below. It's rare to find a product with so many clinical studies.
Protandim Research
Protandim is different from a lot of supplements because there really is clinical research on this product. Below is a summary of the Protandim research with links to the studies for those who want to see them for themselves.
Because scientific studies can be wordy and complicated for most people, I will summarize the study and put the research in the proper context to make it easier to understand.
2016 Protandim Research
Study
The Effect of Protandim® Supplementation on Athletic Performance and Oxidative Blood Markers in Runners.
Study summary: In this investigation, researchers tested if taking Protandim (675 mg/day) for 90 days would improve 5K running performance and reduce TBARS. The study involved 38 runners who were randomly given either Protandim or a placebo.
Results: After 90 days, those taking Protandim (1x/day) showed no improvement in running performance compared to those taking the placebo. In addition, Protandim did not reduce TBARS or alter levels of antioxidant enzymes superoxide dismutase (SOD) or glutathione peroxidase (GPX) during resting periods. The researchers report however that in those over age 35, Protandim improved SOD twice as much as those taking the placebo.
See the full review of this study
Study
Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or an Nrf2-inducer.
Study summary: Here, researchers sought to determine what effect various compounds had on extending the life of mice. Protandim was one of the compounds tested. The other compounds tested in the study were fish oil, ursodeoxycholic acid (a bile acid, used to dissolve gall stones), and the diabetes drug, metformin. Different mice received the different compounds for their entire lifespan.
Beginning at 10 months of age, mice received Protandim at a dosage of 600 parts per million (ppm) in their food. This amount was chosen because it was similar to the Protandim dosage used by people. When the mice were 17 months old, the dosage was increased to 1200 ppm because this was thought to be better.
Study results: researchers noted male mice getting Protandim had a 7% increase in average lifespan. The supplement did not lengthen the life span of female mice. The researchers also point out that while the average lifespan was increased, the maximum lifespan did not increase. Regardless, this was a mouse study.
2013 Protandim Research
Study
Study
Upregulation of phase II enzymes through phytochemical activation of Nrf2 protects cardiomyocytes against oxidant stress
Study results: Researchers noted that mouse heart cells treated with Protandim increased the production of an antioxidant/anti-inflammatory enzyme called Heme oxygenase 1 (HO-1) as well as Nrf2. This was a test-tube study using isolated mouse heart cells.
This investigation is derived from a Masters's Thesis in 2010. The title of the MS Thesis is “UPREGULATION OF HEME OXYGENASE-1 AND ACTIVATION OF NRF2 BY THE PHYTOCHEMICALS IN PROTANDIM .” It is not unusual for a quality MS thesis or other graduate work to go through the peer-review process and be published.
2012 Protandim Research
Study
Antioxidants for the Treatment of Patients with Severe Angioproliferative Pulmonary Hypertension? Published in the journal, Antioxidants in Redox Signaling.
Summary: This is a rat study. Protandim increased antioxidant enzymes in rats, protecting the hearts from damage.
Study
Phytochemical activation of Nrf2 protects human coronary artery endothelial cells against an oxidative challenge published in the journal, Oxidative Medicine and Cellular Longevity.
Summary: This is a test tube study. Human coronary (heart) artery cells were treated with Protandim (20 micrograms per milliliter) or placebo (ethanol). All cells were then treated with hydrogen peroxide (H2O2) to induce free radical damage. Cells treated with Protandim showed less cell death than those getting the placebo.
Study
Protandim does not influence alveolar epithelial permeability or intrapulmonary oxidative stress in human subjects with alcohol use disorders.
Summary: This investigation showed the supplement did not work. To be fair, this was a strange study. Researchers looked at 30 alcoholics . The researchers stuck tubes down the throats of the subjects to take fluid samples from their lungs. They randomly gave the people 1350 mg of Protandim per day or a placebo, for a week. They tested for various things to see if Protandim helped the people. It didn’t.
I don't know how relevant this study is to whether Protandim works or not. I mentioned it because it was a human study. For a much more in-depth review of this study—written by a doctor—see the review posted on ScienceBasedMedicine.org.
2011 Protandim Research
Study
Oxidative stress in health and disease: the therapeutic potential of Nrf2 activation.
Summary: This is a test tube study. Essentially, Protandim altered cellular pathways involved in antioxidant enzyme production and colon cancer, cardiovascular disease (heart disease), and Alzheimer's disease. This is encouraging, but, humans are more complicated than isolated cells. This study doesn’t prove the supplement reduces the risk of any of these diseases.
Study
The role of manganese superoxide dismutase in skin cancer.
Summary: This is a mouse study. Here, researchers reported the supplement reduced tumor growth in mice. For the most part, this appears to be a review of previous research relating free radical damage to the development of skin cancer.
Study
Protandim attenuates intimal hyperplasia in human saphenous veins cultured ex vivo via a catalase-dependent pathway.
Summary. This is a test tube study. Basically, a blood vessel was bathed in Protandim. Researchers noted the supplement reduced the thickening of vein cells.
2010 Protandim Research
Study
The Dietary Supplement Protandim Decreases Plasma Osteopontin and Improves Markers of Oxidative Stress in Muscular Dystrophy Mdx Mice.
Summary. This is a mouse study. Mice were genetically created to have muscular dystrophy. They were given Protandim at a dosage similar to what is recommended for humans. After 6 months, the mice given Protandim showed a 46%reduction in the free radical breakdown of fat (TBARS). TBARS stand for ThiobarBituric Acid Reactive Substances.
The greater the TBAR level, the greater free radical damage. Thus, reducing TBARS is taken to be a good thing. This doesn't prove Protandim helps muscular dystrophy. People with muscular dystrophy should discuss this with their doctor for greater insights.
Study
The chemopreventive effects of Protandim: modulation of p53 mitochondrial translocation and apoptosis during skin carcinogenesis.
Summary: This is a mouse study. Protandim reduced damage to the mitochondria of mouse cells. of this study. The mitochondria, often called the “powerhouse” of the cell, make energy —and makes free radicals in the process. The mitochondria are a major area of anti-aging research.
Study
Chronic pulmonary artery pressure elevation is insufficient to explain right heart failure.
Summary. This is a rat study. Researchers tested if the supplement helped pulmonary blood pressure. After 6 weeks, Protandim did not reduce pulmonary artery blood pressure or the number of lung lesions. These researchers did say “our data point to a cardioprotective effect of Protandim.” But, this is a vague statement.
2009 Protandim Research
Study
Protandim, a fundamentally new antioxidant approach in chemoprevention using mouse two-stage skin carcinogenesis as a model.
Summary: This is a mouse study.
Study
Synergistic induction of heme oxygenase-1 by the components of the antioxidant supplement Protandim.
Summary: This is a test tube study. Cells treated with supplements showed significant increases in glutathione, an antioxidant compound. This is the study LifeVantage lists as “proof” Protandim increases glutathione levels by 300%. It may raise glutathione 300% – in a test tube – but does the same effect occur in people?
2006 Protandim Research
Study
The induction of human superoxide dismutase and catalase in vivo: a fundamentally new approach to antioxidant therapy.
This is a human study. 39 healthy men and women, age 20-78 years were given Protandim (675 mg per day) between 30 and 120 days.
Study Summary:
1. Protandim caused a significant increase in the antioxidant superoxide dismutase (SOD) in red blood cells.
2. TBARS declined by 40% after 30 days
3. SOD in red blood cells increased by 30% after 120 days
4. Catalase decreased by 40% after 120 days
5. There was a non-significant rise (4.9%) in uric acid.
6. No change in CRP levels was seen.
7. No change in HDL, LDL or triglycerides were seen.
Protandim Research Summary
Here is a quick summary of the research:
| Study Year / Title | Study Type (Human, mouse, etc.) |
| 2016 Research | |
| The Effect of Protandim Supplementation on Athletic Performance and Oxidative Blood Markers in Runners | Humans |
| Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer | mice |
| 2013 Research | |
| Upregulation of phase II enzymes through phytochemical activation of Nrf2 protects cardiomyocytes against oxidant stress | Mouse heart cells |
| 2012 Research | |
| Antioxidants for the treatment of patients with severe angioproliferative pulmonary hypertension? | Rats |
| Phytochemical Activation of Nrf2 Protects Human Coronary Artery Endothelial Cells against an Oxidative Challenge | Test tube study |
| Protandim does not influence alveolar epithelial permeability or intrapulmonary oxidative stress in human subjects with alcohol use disorders. | Humans |
| 2011 Research | |
| Oxidative stress in health and disease: the therapeutic potential of Nrf2 activation. | Test tube study |
| The Role of Manganese Superoxide Dismutase in Skin Cancer | Mice |
| Protandim attenuates intimal hyperplasia in human saphenous veins cultured ex vivo via a catalase-dependent pathway | Test tube study |
| 2010 Research | |
| The Dietary Supplement Protandim® Decreases Plasma Osteopontin and Improves Markers of Oxidative Stress in Muscular Dystrophy Mdx Mice | Mice |
| The Chemopreventive Effects of Protandim: Modulation of p53 Mitochondrial Translocation and Apoptosis during Skin Carcinogenesis | Mice |
| Chronic Pulmonary Artery Pressure Elevation Is Insufficient to Explain Right Heart Failure | Rats |
| 2009 Research | |
| Protandim, a Fundamentally New Antioxidant Approach in Chemoprevention Using Mouse Two-Stage Skin Carcinogenesis as a Model | Mice |
| Synergistic induction of heme oxygenase-1 by the components of the antioxidant supplement Protandim. | Test tube study |
| 2006 Research | |
| The induction of human superoxide dismutase and catalase in vivo: a fundamentally new approach to antioxidant therapy. | Humans |
To be fair, it's possible I may have missed some research. I'll update this table as I become aware of new research.
My Thoughts On The Research
While Protandim has been the subject of several clinical investigations, only 3 of them involved humans. They are:
- The 2006 study (click to see study)
- The 2012 study (click to see study)
- The 2016 study (click to see the study)
Protandim And Weight Loss
Can Protaindm help you lose weight? There is no good evidence for this. None of the above clinical investigations was about weight loss. To the credit of LifeVangage, they do not market this supplement for weight reduction.
Protandim And Multiple Sclerosis
Is this supplement worthwhile if you have Multiple sclerosis (MS)? Some have put forth the idea that disruption of free radical stress – via stabilizing Nrf2 (the stuff this supplement is supposed to improve) – might help MS. So, is there any proof? There was an investigation presented in 2011 at the 5th Joint triennial congress of the European and Americas Committees for Treatment and Research in Multiple Sclerosis Amsterdam, The Netherlands.
The title of the presentation was: Nrf2 activators: a novel strategy to promote oligodendrocyte survival in multiple sclerosis? Here, researchers treated rat and human oligodendrocytes with several compounds ― one of which was Protandim ― and then exposed the cells to a chemical to create free radical damage.
These researchers noted Protandim was seen as “the most potent inducer” of Nrf2 antioxidant enzymes defenses. In other words, Protandim helped the most.
This is intriguing, but it's not the same as giving it to people with MS to see if their symptoms improved.
There is also some evidence that stimulating Nrf2 might reduce cellular inflammation via inhibition of NFkb. Inhibition of NFkb is also something another supplement – called Anatabloc – was supposed to do. Currently, though there is little human proof for Protandim improving quality of life in those with MS.
See the Anatabloc review.
Protandim And ABC Primetime
In 2005, this supplement was featured on ABC's Primetime news show. In this segment, ABC correspondent John Quinones met with Dr. Joe McCord, a respected researcher whose name appears on many of the Protandim clinical studies. According to his Wikipedia page, as a grad student, Dr. McCord was involved with the discovery of Superoxide Dismutase, an important free radical savaging enzyme. Here is the ABC Primetime segment :
Basically, John Quinones gets a blood test to measure his TBAR level (an indicator of oxidative stress). He's given Protandim for 2 weeks and then returns to the lab where he has his blood tested again.
Dr. McCord tells John Quinones the supplement caused a “45% reduction” in oxidative stress and goes on to say this is the level seen in a “newborn baby”. The ABC Primetime segment is often used as proof the supplement really works. But, as I see it, one problem is John Quinones doesn't have is blood tested by an independent lab. This is bad science in my opinion.
Of course, the Primetime segment is interesting. But it's been over a decade since this segment aired. You'd think such an impressive result would warrant a follow-up. I wish Primetime and John Quinones would do a follow-up story.
Update. Dr. McCord is now involved with the PB125 supplement.
Protandim And The FDA
In 2017, the FDA reached out to LifeVantage to inform them they considered Protandim to be a drug and not a supplement based on claims made about it as an NRF2 Synergizer. Basically, the FDA was saying the claims being made at the time, made people think the supplement could treat disease. This is something not allowed under US supplement regulation. This may be the reason for the dramatic change in the LifeVantage website and marketing. There are no more claims about the effects of the supplement. Instead, the company now calls itself “a wellness and personal care company” and makes references to “bio-hacking.”
Do Doctors Endorse Protandim?
While the supplement is not endorsed by the American Medical Association (they don't endorse any supplement), I'm sure some physicians believe in it – and others who don't.
Does Protandim Have Caffeine?
According to the product website, each tablet has 1.8mg of caffeine. That's much less than in a cup of coffee and most energy drinks. I don't think this small amount would keep people up at night, but because we are all different it might be wise to not take it close to bedtime.
Is It Kosher?
No. this supplement is not kosher or organic. It is however made in the US. That is good.
Protandim Side Effects
Are there any Protandim dangers out there? I don't think so. I believe this supplement is pretty safe. I am not aware of any side effects. That said, here are a few general things you might want to think about if your not healthy. This list is not complete:
- Start with less than the recommended dosage for the first week to see how you respond
- Speak to your doctor/ pharmacist if you are pregnant or breastfeeding
- Stop taking the supplement at least 2 weeks before having surgery
- Speak to your doctor /pharmacist if you take any prescription drugs like blood thinners
One study noted the supplement might raise uric acid levels (by 4.9%). Would this be bad for those who suffer from gout? Currently, there is no direct proof gout pain is increased by Protandim. See the review of Tart Cherry Juice for more info.
While allergic reactions are likely uncommon, LifeVantage does mention this possibility in some people. Specific symptoms mentioned on the LifeVantage website include:
- gastrointestinal disturbances (i.e., stomach ache, diarrhea, vomiting)
- sometimes as a headache or rash on the hands or feet
Stop taking the supplement if you experience these symptoms.
The company website warns against using the supplement if you are undergoing chemotherapy or radiation therapy for cancer. This is likely because of the unknowns of combining antioxidants with some cancer therapies. If you have cancer or are getting treatment for it, ask your doctor. I'm glad the LifeVantage company informs people about this.
LifeVantage also stresses the importance of talking to a doctor if you have any autoimmune disease like arthritis or Type I diabetes. I'm not aware of any problems in anyone but I appreciated the company mentioning this.
How To Measure Your TBARS
Remember TBARS are a measure of free radical damage (oxidative stress) of cells. Protandim is said to reduce TBARS. The TBAR test is also called a Lipid Peroxidase test. Ask your physician about this test. For those who really want to know if Protandim is working, getting this test done first—and a month later— might be a good idea. I'm not sure if insurance covers the test or not. Talk to your doctor for more information on this.
Aged Garlic Extract also has some evidence it might reduce TBARS (click to see review)
TrueScience Brand
True Science is a brand name under which various beauty products made by the company can be identified. Products offered under the True Science brand include:
- Shampoo
- Scalp serum
- Facial cleanser
- Eye serum
What is PhysIQ?
PhysIQ is the brand name associated with various fitness-related products. This brand includes:
- Fat burn supplements
- Prebiotics
- Whey protein
- Appetite suppressants
Protandim For Dogs
Protandim Dogs (formally called Canine Health) is for pets. According to the LifeVantage website, this supplement contains 150 mg of the same ingredients as Protandim – as well as omega 3 fatty acids and collagen. The website goes on to say: “Reducing oxidative stress in dogs may reduce many of the disorders associated with aging in canine.” To support this, the organization states a 3rd party animal health company has found the supplement reduces oxidative stress in dogs.
Protandim vs. PB125
PB125, by Pathways Bioscience, is another supplement whose makers claim can reduce TBARS and activate NrF2. PB125 is the supplement by Dr. Joe McCord and associates. Recall Dr. McCord used to be associated with the LifeVantage company.
While PB125 is said to be the next generation of NrF2 activators, no studies have yet compared these supplements to each other to see which is better. The ingredients in both products are different for the most part.
See the PB125 Review for much more information.
Protandim vs. Tru Niagen
The Tru Niagen supplement boasts research showing it can raise NAD+ levels in humans. Tru Niagen is based on nicotniamide riboside a form of niacin (vitamin B3).
The idea of slowing aging by raising NAD+ is different than Protandim. So far no clinical studies have compared these supplements to each other. While the original Protandim does not contain nicotinamide riboside, the Life Vantage company does offer another version called the “NAD Synergizer” which contains niacin.
Protandim vs. Elysium Basis
Basis by Elysium is a popular anti-aging supplement that contains very different ingredients than Protandim. Like Tru Niagen, Elysium Basis also is an NAD+ booster supplement. So, which is better? Unfortunately, there are no head-to-head studies yet.
See the Elysuim Basis Review for more insights.
Protandim vs. SeroVital
You've probably seen TV ads for SeroVital. How does Protandim compare to SeroVital? Both supplements contain different ingredients and are touted to work differently.
While Protandim is said to help boost our bodies antioxidant enzymes, SeroVital is marketed to raise human growth hormone (HGH).
If we just look at the research, Protandim wins hands down. The makers of Serovital only have one study.
Where To Buy Protandim
This supplement is not sold in stores like Walmart, Target, Cosco, CVS, Walgreens, Kmart, or BJs. It's also not sold at GNC or Vitamin Shoppe. Rather, it's mostly purchased from LifeVantage independent distributors.
It is also available online as well although when using a distributor, you may get the individualized attention you might not get by buying it yourself.
Protandim Price
According to the LifeVantage website, a one-month supply (30 capsules) costs $59.99 retail. If you order it through a LifeVantage distributor, it costs $49.99 – and that is on a monthly basis. In other words, that means auto-shipments. If you want to purchase one month only to test drive it first, speak to your LifeVantgage independent distributor.
Protandim Yearly Cost
Let's round the price up to $50 a month. In one year, the supplement would cost you $600. Shipping and tax may be extra. If you only want to order 1 bottle to try yourself, you can get it on Amazon too.
My Suggestions
If you can afford it, go ahead and give it a try for a month or so and see if you feel any better. If you really want to know for sure, get your TBARS measured first.
Remember, exercise will also reduce TBARS too.
Protandim Pro & Con
Here's a quick summary of what I liked and didn't like. These are my opinions. Yours may be different.
| Pro | Con |
|---|---|
| There are clinical studies on Protandim | Not all the studies are on humans |
| Company has been around a long time | Not available in stores |
| Company sponsors research on Protandim | Expensive |
| Lots of hype about benefits |
Does Protandim Work?
While I'm intrigued at the prospect of slowing down aging, I'm can't say for sure if Protandim works or not. The research is intriguing but in my opinion three's not enough human research yet to draw conclusions. So, does Protandim really work? Let's just say I'm looking forward to more human clinical studies.
Here is it is on Amazon If you want to check it out/see what others are saying
Yes you were supposed to read the white papers I sent you the link, Protadim isn’t worth talking about.
http://www.kyaniscience.com/en-us/research.html
I’m sorry but your complete ignorance and knowledge has now been made available to all, you stated
“Arginine is simply an amino acid and it is an essential precursor of nitric oxide. The body cannot produce nitric oxide without arginine. It is present in a wide variety of foods and deficiency of arginine in the diet is pretty much unheard of. The minuscule amount of noni in Kyani’s products is virtually worthless; it certainly would have no effect on nitric oxide output.( you obviously do not know what your talking about.)
The amino acid arginine was the first recognized precursor of nitric oxide synthesis. A metabolic pathway catalyzed by enzymes called nitric oxide synthases (NOSs) converts arginine to nitric oxide through a complex five-step process. However, in 1994 it was found by two independent research groups that nitric oxide could be made independent of the NOSs and arginine (6,7). These groups found that ingestion of nitrates greatly enhanced production of nitric oxide. High concentrations of nitric oxide are produced from nitrates by the acidity in the stomach. This process depends, in part, on nitrites derived from saliva. In the gastrointestinal tract, circulation of nitrogen containing molecules occurs in the following manner: Any nitrates that escapes conversion to NO in the stomach enters the circulation or passes into the small intestine and is absorbed into the circulation; subsequently nitrates are delivered to the salivary glands and the saliva containing nitrates are actively secreted into the mouth. Bacteria in the mouth then convert (“reduce”) nitrates to nitrites (8). The process of nitrate reduction also occurs in the heart (9) and multiple other organ systems throughout the body.
Luke said: “I thought you were the kind of guy that did research – arginine is animal protein based from chicken feathers out of China and has side effects. The botanical pathway from Noni is thousands of times more potent.”
Arginine is simply an amino acid and it is an essential precursor of nitric oxide. The body cannot produce nitric oxide without arginine. It is present in a wide variety of foods and deficiency of arginine in the diet is pretty much unheard of. The minuscule amount of noni in Kyani’s products is virtually worthless; it certainly would have no effect on nitric oxide output.
Luke said: “Dr. Joe is the creator of ProArgi-9 Plus formula which includes organic L-arginine, L-citrulline. He and the other co formulator left that company because Kyani is far better.”
Oh lord! You do realize that this article is about Protandim, not Kyani? If you want to plug Kyani instead, how about you write your own article elsewhere and I’ll drop by there to eviscerate it. Fair enough?
Luke said: “You clearly did not read the white papers.”
Was I supposed to? What white papers?
Luke said: “The Dr that sit on the board that made this product are all PH.D. Their research is based on accepted science.”
The product they are selling is mundane MLM-pyramid scheme snakeoil BS, based not on science but on greed and the assumption that people are idiots. You’re fooling no one.
I thought you were the kind of guy that did research – arginine is animal protein based from chicken feathers out of China and has side effects. The botanical pathway from Noni is thousands of times more potent.
The entire board of the Company Synergy left including Dr Joseph Pendergast
Dr. Joe is the creator of ProArgi-9 Plus formula which includes organic L-arginine, L-citrulline. He and the other co formulator left that company because Kyani is far better.
You clearly did not read the white papers.
The Dr that sit on the board that made this product are all PH.D. Their research is based on accepted science.
all I can say is oh boy that’s quite the list, this stuff should have a patent (eye roll)
Day 1: 2015-09-30 (I am 65 years old and in very bad health).
1 pm (time ⌚ ingested, approximate time here and for the following).
First evening, I think I “feel” something is happening inside my body. Positive feeling. “But it must be in my head…” (yet, I did not really believe in this Product but since it is totally natural – no chemicals – safe try it).
Late. Felt very sleepy in a surprising way.
___
Day 2: 2015-10-01
11:30
Shortly after ingesting, stomach became uncomfortable. Realized that the supplement requires food.
Coffee (French bean roasted) had an inferior taste. Drank one cup only. The rest was left in the Pot and thrown away. Why? I love nice freshly Dark French grinded black coffee. It’s delicious, yet, my loss of coffee delight has vanished. (I can hardly believe this, frankly).
During the afternoon, yawning. Surprising. I never “yawned” but my body tells me that I am tired. Nice message.
Evening. My usual snack would be fresh Canadian Cheddar cheese with crackers, European Salami and pitted olives. Couldn’t take more than 3 bites. Absolutely not hungry. First time that I had no need of this type of snack in decades.
End of day, slight headache in the lower back of my head. Very unusual for me.
___
Day 3: 2015-10-02
11h
Coffee not desired.
In the afternoon until 8pm, I urinated at least 12 times. (I spoke with an informed Distributor of Protandim and he simply said that I was “flushing”). In essence, the many poisons in my body were being released. To me, it made sense.
End of day, not hungry, no snacks. No beers. Zero interest. (What the frack is happening to me )
___
Day 4: 2015-10-03
Time noon
Did not need coffee
Tired ? at 11:30 pm
Went to bed. Slept soundly. That is weird. I usually go to bed between 2 am and 4 am.
Only got up once to urinate during the night. (Usually 4 times to 5 times).
Suffering from Chronic Anxiety, I always wake up with horrid dark thoughts and my first hour, I was a zombie, running first and foremost for my medications. This morning, got up with a great attitude, positive, chatted with my wife, we laughed and took my meds 1h30 after being up. This is amazing and revolutionary for me.
Took Protandim with half a banana ? and no stomach discomfort.
That is when I decided that I want to help others… and I became a Distributor of Protandim Life Vantage. Getting excited. I CAN make a difference.
Slight headache in the lower back of my head but not as strong as last night. (This will be the last slight headache ever).
___
Day 5: 2015-10-04
10:30
Wow. I always used to have “frozen feet” when going to bed, sometimes with an extra blanket or two and 3 pairs of thick cotton socks and that, still, was not enough… My feet were freezing. (Bad blood circulation).
Now, I don’t have frozen feet at all and can sleep comfortably without socks. This is of great importance. It means that my blood circulation is getting back to normal… in only 5 days. I have had this issue for many many years. Totally amazing! And this is not in my head. This is a “physical” change. Outstanding!
IMPORTANT: I had very bad knees. The specialists told me that I needed two knee transplants. My pain was bad. I was walking with a cane with knee straps. Today, I realized that my knees no longer hurt. W.H.A.T.??? They don’t. I don’t need a cane to walk.
Also, I was weak because of my knees and could not do any heavy lifting. Now, I feel I am 25 years younger. I work hard physically, I can axe wood and carry it. I can clean the beach… and I want to do physical work. This is outstanding to me. Truly. Please trust me. I am not making this up.
___
Day 6: 2015-10-05
9:30
I am in a great humor the moment I get up in the morning. Totally awesome!
___
From day 7, I will no longer count the days, only the side effects.
My first client, (Name withheld) just informed me that after taking Protandim for 3 days, her acute hip arthritis pain that she has been suffering daily for years has disappeared completely, her vision, as per her Ophthalmologist, no longer has the previous progressive glaucoma, and her moral has totally changed from daily wake ups with Dark thoughts to gone and replaced with encouraging thoughts. At last, she can take walks again.
___
My wife (name withheld) is no longer depressed (a long standing conditions for all of her life) and no more blood spots on her skin (especially her arms) even if she did hit herself this week. Her skin seems also younger. Not depressed, happy daily, full of energy and no blood spots. This has not happened for years. She never wanted to take any pills but seeing the changes Protandim did for me, she decided to start using this natural supplement. She has totally changed for far better… WOW. (I can hardly believe it).
___
After about 15 days, I realized that my eyesight is slowly getting better too. Never could I read anything on the Internet or in emails (via my Computer screen) without my glasses prior to Protandim. Now, I find that each day, the blur of my eyesight (without glasses) is slowly but surely disappearing (partially, at least).
I just took my glasses off and I can read what I am writing. This was impossible before. I shall continue to write this Journal without glasses.
___
(My wife) feels a general well-being. Her depressing state remains gone and she is full of “pep” (energy) and dark thoughts are gone… daily. Outstanding! Do you know how much a husband pains when his beloved wife is “down” or “depressed”. I always thought, from our first “yes, I do”, that my job was to make her happy, daily. Yet, this chronic issue was always present to a certain degree… and it made me feel a FAIL as a husband. I adore her. Now, simply with Protandim, things are changed. Can you imagine what this is doing to me… 😉
___
My wife (64 years old) used to have blood spots on her forearms and elsewhere for decades. A simple slight bump would create a blood spot and that would last weeks. Since she is on Protandim, all her blood spots have TOTALLY disappeared and for the past few moments (days) of taking Protandim, not one single spot reappeared. First time in years… no blood spot. Her skin also seems softer, younger.
___
We are now 1 month of taking Protandim. All the benefits listed above remain… to my surprise. We were at our cottage for a while (left for a weekend and ended up staying there for over 6 weeks) and we were out of Protandim. Both my wife and I started to feel a huge difference without Protandim. Yet, Protandim is not addictive. It is made exclusively from natural ingredients (green tea, milk white thistle (that plant that allows the Monarch Butterfly to live), ginseng, and two extracts of plants from India and China, used for thousands of years as a health supplement. We can’t be addictive to it. But our addiction comes from our quality of life. We missed it so much that I had a bottle shipped directly to our cottage… We don’t want to be without this amazing product.
___
Personal Journal off:
NOTICE TO ALL: Protandim has different effects on all. We are all unique individuals. If your health is good, then, using Protandim will NOT necessarily give you those amazing changes that it gave us. We were in poor health. If you are in good health, you will probably not notice any changes in your body.
Simply remember that Protandim is made of natural elements that God gave us and after 40 years of research, a special PhD Specialist came up with the exact quantities in millimetres of the exact 5 natural products produced on earth and that was the basis of Protandim.
Two other individuals (wonderful and generous guys – helping Children in Poverty all over the world) who were working with the original Scientist put the ingredients together and created the caplet and they are the “Inventors” of Protandim but without the 40 year of research from this original Doctor (now in retirement), this would never have been discovered.
Protandim has a simple function. It simply nourishes each of our trillions of cells to produce the combating enzymes against “free radicals”. Free radicals are the enemy of our cells. The younger one is, the more “good enzymes” fight the “free radicals”… but as time passes, the good enzymes are overtaken by free radicals and that is when we get sick… cancer, heart issues, diabetic, and think of any other sickness in existence. Protandim gives our cells the elements to multiply by millions the good enzymes and therefore, the battle remains longer and successful to repulse the overcoming of free radicals.
Protandim is not a magic pill, it will not “cure” established diseases and it will not give you Eternal Life.
What Protandim does is offer you a quality of life, longer than if you did not take it. The earlier one takes it, the better. You don’t have to feel any different. You simply have to read, beyond the negative articles and websites against Protandim and do your own research and in the end, you will realize that Protandim is a revolutionary discovery at the scale of Insulin of not beyond.
It is new and our human nature is “naturally” against anything that is revolutionary… but we generally find that a “revolutionary” product happens once in a lifetime. In my case, I lived through 2 “revolutionary” products. The introduction of the Personal Computer… and Protandim.
Philippe Paquette
Philippe Paquette said: “Felt very sleepy in a surprising way…my loss of coffee delight has vanished… Surprising. I never “yawned”…Absolutely not hungry…I was “flushing…the many poisons in my body…Only got up once to urinate during the night. (Usually 4 times to 5 times). Suffering from Chronic Anxiety…This morning, got up with a great attitude, positive…This is amazing and revolutionary for me…I became a Distributor of Protandim Life Vantage…Now, I don’t have frozen feet at all and can sleep comfortably without socks…my blood circulation is getting back to normal… in only 5 days…I had very bad knees. The specialists told me that I needed two knee transplants…Today, I realized that my knees no longer hurt…Now, I feel I am 25 years younger… My first client just informed me that after taking Protandim for 3 days, her acute hip arthritis pain…disappeared completely…no longer has the previous progressive glaucoma…At last, she can take walks again….My wife (name withheld) is no longer depressed (a long standing conditions for all of her life) and no more blood spots on her skin…I realized that my eyesight is slowly getting better too.”
Oh, is that all? Protandim cured depression, anxiety, arthritis, overactive bladder, poor circulation, glaucoma, blood spots, etc.? In only 7 days you say? You know that, as a distributor, it’s illegal for you to make such claims, aside from the fact that they are completely implausible? Ooo, and let me guess – your wife’s name, which you withheld (for some odd reason) is “Mrs. Paquette”?
Philippe Paquette said: “I actually don’t care what anyone says. What I care about is me. My health. Period.”
Obviously that’s not true or you wouldn’t have wasted the effort to break the law and post that moronic promotional essay here.
Philippe Paquette said: “Simply remember that Protandim is made of natural elements that God gave us and after 40 years of research, a special PhD Specialist came up with the exact quantities in millimetres of the exact 5 natural products produced on earth and that was the basis of Protandim.”
No, Protandim did not arise as a result of 40 years of research. It came about as a result of a month or two of last-minute scrambling by Paul Myhill (who most certainly does not have a PhD) to find a replacement product after LifeLine Therapeutics’ deal to market a peptide (CMX-1152) made by Ceremedix (the product originally designated to be Protandim) fell through. It’s all in the public record.
Philippe Paquette said: “Protandim is not a magic pill, it will not “cure” established diseases and it will not give you Eternal Life.”
Well now I’m truly confused, because that BS fairy tale you penned was designed to convey precisely that it is a magic pill and that it cured (or at least significantly mitigated) at least half a dozen serious diseases.
Philippe Paquette said: “You simply have to read, beyond the negative articles and websites against Protandim and do your own research and in the end, you will realize that Protandim is a revolutionary discovery at the scale of Insulin of not beyond… In my case, I lived through 2 “revolutionary” products. The introduction of the Personal Computer… and Protandim”
Wait, didn’t you just say it’s not a magic pill, and yet now you’re comparing it to insulin and the invention of the PC? WTF? You represent everything that’s wrong with this BS snakeoil pyramid scheme. It’s clear why you would try to steer people away from reading “negative” websites as you call them (i.e., well founded factual critiques) – it’s to serve your own financial interest; nothing more. You should be embarrassed and ashamed of yourself.
Protandim and “my” subjective truth.
Some say that the 5 natural elements of Protandim are not effective and the entire thing is a SCAM.
I actually don’t care what anyone says. What I care about is me. My health. Period.
I have been taking Protandim daily for the past month. I did not have a good health. Allow me to share my truth. Of course, it is my view, thus, subjective. Yet it is the truth and that is all that counts (at least for me).
_______
Day 1: 2015-09-30 (I am 65 years old and in very bad health).
1 pm (time ⌚ ingested, approximate time here and for the following).
First evening, I think I “feel” something is happening inside my body. Positive feeling. “But it must be in my head…” (yet, I did not really believe in this Product but since it is totally natural – no chemicals – safe try it).
Late. Felt very sleepy in a surprising way.
___
Day 2: 2015-10-01
11:30
Shortly after ingesting, stomach became uncomfortable. Realized that the supplement requires food.
Coffee (French bean roasted) had an inferior taste. Drank one cup only. The rest was left in the Pot and thrown away. Why? I love nice freshly Dark French grinned black coffee. It’s delicious, yet, my loss of coffee delight has vanished. (I can hardly believe this, frankly).
During the afternoon, yawning. Surprising. I never “yawned” but my body tells me that I am tired. Nice message.
Evening. My usual snack would be fresh Canadian Cheddar cheese with crackers, European Salami and pitted olives. Couldn’t take more than 3 bites. Absolutely not hungry. First time that I had no need of this type of snack in decades.
End of day, slight headache in the lower back of my head. Very unusual for me.
___
Day 3: 2015-10-02
11h
Coffee not desired.
In the afternoon until 8pm, I urinated at least 12 times. (I spoke with an informed Distributor of Protandim and he simply said that I was “flushing”). In essence, the many poisons in my body were being released. To me, it made sense.
End of day, not hungry, no snacks. No beers. Zero interest. (What the frack is happening to me )
___
Day 4: 2015-10-03
Time noon
Did not need coffee
Tired ? at 11:30 pm
Went to bed. Slept soundly. That is weird. I usually go to bed between 2 am and 4 am.
Only got up once to urinate during the night. (Usually 4 times to 5 times).
Suffering from Chronic Anxiety, I always wake up with horrid dark thoughts and my first hour, I was a zombie, running first and foremost for my medications. This morning, got up with a great attitude, positive, chatted with my wife, we laughed and took my meds 1h30 after being up. This is amazing and revolutionary for me.
Took Protandim with half a banana ? and no stomach discomfort.
That is when I decided that I want to help others… and I became a Distributor of Protandim Life Vantage. Getting excited. I CAN make a difference. (I am being transparent here for this webiste).
Slight headache in the lower back of my head but not as strong as last night. (This will be the last slight headache ever).
___
Day 5: 2015-10-04
10:30
Wow. I always used to have “frozen feet” when going to bed, sometimes with an extra blanket or two and 3 pairs of thick cotton socks and that, still, was not enough… My feet were freezing. (Bad blood circulation).
Now, I don’t have frozen feet at all and can sleep comfortably without socks. This is of great importance. It means that my blood circulation is getting back to normal… in only 5 days. I have had this issue for many many years. Totally amazing! And this is not in my head. This is a “physical” change. Outstanding!
IMPORTANT: I had very bad knees. The specialists told me that I needed two knee transplants. My pain was bad. I was walking with a cane with knee straps. Today, I realized that my knees no longer hurt. W.H.A.T.??? They don’t. I don’t need a cane to walk.
Also, I was weak because of my knees and could not do any heavy lifting. Now, I feel I am 25 years younger. I work hard physically, I can axe wood and carry it. I can clean the beach… and I want to do physical work. This is outstanding to me. Truly. Please trust me. I am not making this up.
___
Day 6: 2015-10-05
9:30
I am in a great humor the moment I get up in the morning. Totally awesome!
___
From day 7, I will no longer count the days, only the side effects.
My first client, (Name withheld) just informed me that after taking Protandim for 3 days, her acute hip arthritis pain that she has been suffering daily for years has disappeared completely, her vision, as per her Ophthalmologist, no longer has the previous progressive glaucoma, and her moral has totally changed from daily wake ups with Dark thoughts to gone and replaced with encouraging thoughts. At last, she can take walks again.
___
My wife (name withheld) is no longer depressed (a long standing conditions for all of her life) and no more blood spots on her skin (especially her arms) even if she did hit herself this week. Her skin seems also younger. Not depressed, happy daily, full of energy and no blood spots. This has not happened for years. She never wanted to take any pills but seeing the changes Protandim did for me, she decided to start using this natural supplement. She has totally changed for far better… WOW. (I can hardly believe it).
___
After about 15 days, I realized that my eyesight is slowly getting better too. Never could I read anything on the Internet or in emails (via my Computer screen) without my glasses prior to Protandim. Now, I find that each day, the blur of my eyesight (without glasses) is slowly but surely disappearing (partially, at least).
I just took my glasses off and I can read what I am writing. This was impossible before. I shall continue to write this Journal without glasses.
___
(My wife) feels a general well-being. Her depressing state remains gone and she is full of “pep” (energy) and dark thoughts are gone… daily. Outstanding! Do you know how much a husband pains when his beloved wife is “down” or “depressed”. I always thought, from our first “yes, I do”, that my job was to make her happy, daily. Yet, this chronic issue was always present to a certain degree… and it made me feel a FAIL as a husband. I adore her. Now, simply with Protandim, things are changed. Can you imagine what this is doing to me… 😉
___
My wife (64 years old) used to have blood spots on her forearms and elsewhere for decades. A simple slight bump would create a blood spot and that would last weeks. Since she is on Protandim, all her blood spots have TOTALLY disappeared and for the past few moments (days) of taking Protandim, not one single spot reappeared. First time in years… no blood spot. Her skin also seems softer, younger.
___
We are now 1 month of taking Protandim. All the benefits listed above remain… to my surprise. We were at our cottage for a while (left for a weekend and ended up staying there for over 6 weeks) and we were out of Protandim. Both my wife and I started to feel a huge difference without Protandim. Yet, Protandim is not addictive. It is made exclusively from natural ingredients (green tea, milk white thistle (that plant that allows the Monarch Butterfly to live), ginseng, and two extracts of plants from India and China, used for thousands of years as a health supplement. We can’t be addictive to it. But our addiction comes from our quality of life. We missed it so much that I had a bottle shipped directly to our cottage… We don’t want to be without this amazing product.
___
Personal Journal off:
NOTICE TO ALL: Protandim has different effects on all. We are all unique individuals. If your health is good, then, using Protandim will NOT necessarily give you those amazing changes that it gave us. We were in poor health. If you are in good health, you will probably not notice any changes in your body.
Simply remember that Protandim is made of natural elements that God gave us and after 40 years of research, a special PhD Specialist came up with the exact quantities in millimetres of the exact 5 natural products produced on earth and that was the basis of Protandim.
Two other individuals (wonderful and generous guys – helping Children in Poverty all over the world) who were working with the original Scientist put the ingredients together and created the caplet and they are the “Inventors” of Protandim but without the 40 year of research from this original Doctor (now in retirement), this would never have been discovered.
Protandim has a simple function. It simply nourishes each of our trillions of cells to produce the combating enzymes against “free radicals”. Free radicals are the enemy of our cells. The younger one is, the more “good enzymes” fight the “free radicals”… but as time passes, the good enzymes are overtaken by free radicals and that is when we get sick… cancer, heart issues, diabetic, and think of any other sickness in existence. Protandim gives our cells the elements to multiply by millions the good enzymes and therefore, the battle remains longer and successful to repulse the overcoming of free radicals.
Protandim is not a magic pill, it will not “cure” established diseases and it will not give you Eternal Life.
What Protandim does is offer you a quality of life, longer than if you did not take it. The earlier one takes it, the better. You don’t have to feel any different. You simply have to read, beyond the negative articles and websites against Protandim and do your own research and in the end, you will realize that Protandim is a revolutionary discovery at the scale of Insulin of not beyond.
It is new and our human nature is “naturally” against anything that is revolutionary… but we generally find that a “revolutionary” product happens once in a lifetime. In my case, I lived through 2 “revolutionary” products. The introduction of the Personal Computer… and Protandim.
Philippe Paquette
Luke said: “Look up company called Kyani they make no health claims but look on YouTube type in Kyani and MS or any other thing you might be interested in, this is something real.”
Something real ridiculous?
I had a look at their Triangle of Health Pack, basically a mundane multivitamin combo with some Noni juice selling for the insanely high price of $156.95 for a 30-day supply. Typical ripoff MLM scam – i.e., mundane products, crazy markup to support the pyramid, and marketing rife with hyperbole and outright BS.
https://shop.kyani.net/en-us/#/products/101ENHTP30/kyani-triangle-of-health-pack-packets
They don’t sell any products for MS; the very mention of MS in the same breath as this snakeoil is offensive.
Luke said: “They only have 3 products all 3 work together to give your body what it needs — if you look up Nitric Oxcide you’ll see the benefits of that, Kyani has the most potent Precursor to stimulate your body to produce it.”
You presumably meant nitric oxide, not “Nitric Oxcide”. I also presume that the product you’re referring to is Kyani NitroFX. I had a look at the product’s ingredient label and noticed that it didn’t contain any potent nitric oxide precursors. I had expected to see that it contained arginine, which is a nitric oxide precursor as well as a dirt cheap ingredient and a common component of supplements that allege to enhance nitric oxide production (like those fake herbal boner pills they sell at gas stations and convenience stores), but NitroFX didn’t even contain that. All it has is a mundane patchy mix of minerals (scant amounts of magnesium, zinc, and chromium at less than 10% of RDA), vitamin B1, niacin (an insignificant amount), some CoQ10, and a tiny bit of noni juice extract (80 mg).
http://kyaniinformation.joinhomebiz.com/products.html
This stuff is next to worthless, but Kyani is selling a 2 mL bottle (a 30-day supply) for $56 (tax and shipping not included).
http://www.kyanihawaii.com/kyani-nitro-fx.html
I hate to see new snakeoil scams like this trying to make inroads.
They only have 3 products all 3 work together to give your body what it needs — if you look up Nitric Oxcide you’ll see the benefits of that, Kyani has the most potent Precursor to stimulate your body to produce it.
Luke, I saw quite a few different NO products as well as products called “sunrise” and “sunset” 3 products called the “triangle of health” Ive looked at nitric oxide boosters. Most of the research I see on NO involves people with angina and “ED.” I looked at its ingredients and while some of the ingredients might transiently raise NO, Id say exercise is probably a better way. For those looking for a supplement, turmeric also has some research too.
Look up company called Kyani they make no health claims but look on YouTube type in Kyani and MS or any other thing you might be interested in, this is something real.
Luke, I looked them up. They have several products. Which product do people say helps MS?
That study has been discussed several times on this site, and probably with Greg B involved. It’s just another (illegal) attempt to imply that Protandim is a treatment for MS, which it is not.
Joe, did you ever see this? http://registration.akm.ch/einsicht.php?XNABSTRACT_ID=137548&XNSPRACHE_ID=2&XNKONGRESS_ID=150&XNMASKEN_ID=900
Hi Greg, yes I have seen it. I linked to it in my review. It looks like a study of rat brain cells. Interesting stuff. Would love to see a study of people with MS to see what happens.
Greg, you know full well that we have discussed this abstract already many times over, so why are you still beating this dead horse?
The Protandim shills here have repeatedly posted links to the abstract, stating at the beginning of 2013:
By Simone in February 2013:
http://supplementclarity.com/protandim-research-review-lifevantage/comment-page-5/#comment-72379
By JD on April 19, 2013:
http://supplementclarity.com/protandim-research-review-lifevantage/comment-page-14/#comment-75216
By Sharon on August 16, 2013:
http://supplementclarity.com/protandim-research-review-lifevantage/comment-page-20/#comment-79166
By Patsrick1943 on Jan 3, 2015 and June 4, 2015:
http://supplementclarity.com/protandim-research-review-lifevantage/comment-page-37/#comments
http://supplementclarity.com/protandim-research-review-lifevantage/comment-page-2/#comment-102789
And now, for some inexplicable reason, Greg B has re-posted the link yet again, pretending that it’s novel despite the fact that the Joe wrote about it in the body of his review, and that the abstract was debunked on several occasions spanning the last few years:
http://supplementclarity.com/protandim-research-review-lifevantage/comment-page-29/#comment-85666
http://supplementclarity.com/protandim-research-review-lifevantage/comment-page-37/#comment-96001
http://supplementclarity.com/protandim-research-review-lifevantage/comment-page-37/#comment-95994
http://supplementclarity.com/protandim-research-review-lifevantage/comment-page-37/#comment-95974
Why are you still wasting our time with this crap Greg? The abstract came out in 2011. More than 4 years have passed and this “study” has still never been published as a full peer-reviewed research article. Want to know why? Because it’s unpublishable crap, not worthy of even the faintest consideration. But that won’t stop Protandim distributors from deceptively using it in their attempts to con people into believing that Protandim is a remedy for MS. Shame on you all.
Gotta love people who refuse to read what other people have written, call them ignorant, write a bunch of ill informed and misleading nonsense, and then declare “case closed.” Nice try.
All Health Canada has done is allow the product to be sold after looking at what the ingredients are, and what claims are (officially) made about the product. The less significant the health claims are, the lower the standard of evidence is required. Claiming to reduce oxidative stress is not much of a claim, so very little supportive evidence was required to get licensed.
Health Canada did not conduct any testing, and it is misleading of you to suggest otherwise. They looked at the ingredients and whatever studies Lifevantage submitted in order to get approval. Since no disease claims are officially being made, the bar is pretty low to qualify for approval.
Furthermore, even when a disease or health claim has been made by a supplement company, the process of getting approved for a license from Health Canada has been called a joke. A bogus fever remedy with no scientific proof was submitted to test the validity of the licensing process, and it got approved. Read this: http://www.cbc.ca/m/news/health/health-canada-licensing-of-natural-remedies-a-joke-doctor-says-1.2992414
As for “case closed,” how is this: the person who “invented” Protandim (Paul Myhill) doesn’t take it anymore. What more would anyone need to know?
It would be a waste of time for me to read all the responses here. I had enough of the Original Article that most certainly demonstrates the ignorance of the writer.
Protandim has been approved by Health Canada. They have 3 criteria to allow an approval imprinted on any Natural Supplements:
a) Is the Product “SAFE”?
b) Is the Product “EFFECTIVE”?
c) Is the Product of “HIGH QUALITY”?
Health Canada’s mandate is far wider than the American FDA’s mandate that deals with DRUGS, not “natural supplements”. So it would be idiotic for Life Vantage to seek FDA’s approval because they can not get it.
On the other hand, Health Canada’s mandate is to evaluate (test, etc.) all Products that are consumed by humans. All of them, no only Drugs.
Health Canada gives a “NPN” number on the Products that have been shown to be “SAFE”, “EFFECTIVE” and “HIGH QUALITY”. It is always an 8 digit number followed by the NPN appellation (stands for Natural Product Number).
Protandim has (at least in Canada) this NPN number:
NPN 80040726
Health Canada (a Department of the Government of Canada) is a world renown authority and they have attested that Protandim is “SAFE”, “EFFECTIVE” and “OF HIGH QUALITY”.
Case closed.
Philippe Paquette
Philippe, How is it ignorant to help people understand the research?
I looked up Protandim on the Health Canada website. here is the link:
http://webprod5.hc-sc.gc.ca/lnhpd-bdpsnh/info.do?licence=80040726&lang=eng
I do appreciate you telling me about this because it does give details on how much of each ingredient is in protandim. I have updated my review with that information.
Snore! Protandim is in the same Health Canada “recommended use” category (i.e., “antioxidant”) as 10,948 other supplement products, including just about every mundane formulation of vitamin C and vitamin E on the market, all of which sell for about a tenth or less of what Pretendumb costs.
This is the kind of grasping at straws that the company continually resorts to in order to deceive consumers into thinking that their scam is legit. The weight of evidence against them though is absolutely crushing, and an entry for the product in the Health Canada supplement database doesn’t change that one iota.
Hey Vogel maybe they’re right hey when all else fails you’ve got nothing else to lose, you’ll die anyway in the end may as well make a quick buck mlm or not, who really cares in the end? The market is there, the believers are there.
Mike Davies said: “A study I recently found that the University of Montreal was involved in.”
Correction: you mean a study that was done by a Master’s student at University of Montreal.
Old news. We discussed this way back in April.
http://supplementclarity.com/protandim-research-review-lifevantage/#comment-101125
http://supplementclarity.com/protandim-research-review-lifevantage/#comment-101146
http://supplementclarity.com/protandim-research-review-lifevantage/#comment-101164
Yes, the university was involved in this study. A student there conducted the study, meaning that he used university space and equipment. Even more, he was taught and supervised during this study by university professors.
The fact that the study went on to be published means that his professors approved of the study and its findings. I would be willing to bet money that the student received an A for this.
So while it would be inaccurate to say that the University of Montreal conducted the study, that is not what Mr Davies said. He said that the university was “involved”, which is entirely accurate.
Just scroll down it’s in English I think there was some discussion about this article previously…..
Thanks! That’s what I get for not scrolling down 🙂
A study I recently found that the University of Montreal was involved in.
https://papyrus.bib.umontreal.ca/xmlui/handle/1866/11778
Mike, thanks. It looks like its in french so I will have to search for the English version.
I understand what you mean but you stated that the study summary did NOt say it was done one mice when if fact it was spelled out in acceptable scientific terminology as it is a scientific article. Your statement on what was written on the abstract isn’t correct and implied deceit by the authors.
Again, you also need be aware of the publication categories in science as you criticized the lack of data available to the reader in a review paper. If you’re simplifying scientific literature to your readers you cannot use the differences to point out flaws. I know you wanted to point out it was done on mice but you criticized the lack of data too which is not necessary in a review article. This review article is available in .pdf format as it was printed and the Review categorization is stated there.
Ps. I don’t use this product nor am I involved in anything with this company whatsoever. I only wanted to comment on your interpretation on the science of this compound based on my humble scientific knowledge and how I think you’re not accurate.
Adriana T, it was not my intention to imply any deceit. My words reflect my opinions when I read the article. That’s all there was to it. I truly do appreciate your feed back although I feel I was accurate in my descriptions of the research.
Regarding the article : “The Chemopreventive Effects of Protandim: Modulation of p53 Mitochondrial Translocation and Apoptosis during Skin Carcinogenesis” you wrote:
Summary: This is a mouse study. Interestingly the word “mouse” never appears in the summary of this study. You have to read the actual study to see that it used lab mice. Protandim reduced damage to the mitochondria of the mouse cells.
Just FYI. Murine refers to mouse/rodent and scientifically speaking (it is a scientific journal after all) it is appropriate to use it on the abstract of any research paper. This study uses the word “murine” to refer to the model used in their study. Nothing new or remotely deceitful using the term murine in the scientific world.
Also, regarding the review article titled: “The role of manganese superoxide dismutase in skin cancer” you wrote:
Summary: This is a mouse study. I found this study strange because, for the most part, it appears to be a review of previous research relating free radical damage to the development of skin cancer. The actual study isn’t even discussed until you have read half of the paper—and then it’s only a vague description of the research. In the study, researchers reported that Protandim reduced tumor growth in mice. But, how much Protandim did the mice get? If that information is in the study, I could not find it.
Just FYI, that is a REVIEW article meaning it’s a summary and/or opinion on already published data. It doesn’t present new data as it doesn’t have to. It says, right at the top of the title that it is a review article, which as it’s name implies it’s an analysis of what’s out on the literature. There is no information not being disclosed as you suggest with your questions.
Adriana T., thanks for writing. Let me try to address your concerns: I wrote my review the way I did, because when Protandim was originally presented to me, it was done so using lots of big words and lots of research. For the average person, I felt it was overwhelming. Distributors basically told people to “go to pubmed” to see the research. I felt this was too much for the busy, average person with no science background to do. As such I tried to make my interpretation of the research as easy as I could to help people better be able to take it all in. Hence the use of the word “mouse” as opposed to “rodent.”
As for the second article you cited, ““The role of manganese superoxide dismutase in skin cancer” I don’t see the word “review” in the title. Regardless, if it’s a review article or not, it involved mice. Again, I only wanted to give people something easy to digest to help them better form opinions.
I hope that clears things up.
A couple whom I know fairly well have given their lives to this company and the product. My concern is, he’s a practicing heart surgeon and is giving lectures on the advantages of using this product. So either this couple is making some hellish money or the product is that good. I don’t know and I’ve given it over a years thought. Any comments? Thanks
Janisum, I can’t comment on your friend. I prefer to stick to the research and leave it at that.