Procera Protect (Ceraplex) is said to provide the brain with natural antioxidants to support detoxification pathways for maintenance of good brain health. That's what the company says about this cognitive enhancement supplement.
Sounds good, but does Procera Protect work? In this review, I'll reveal the ingredients and science behind them and also help you understand if this supplement is right for you. For more insights see the reviews on Procera AVH, and Nerium EHT and Prevagen
What Is This Procera Protect?
The supplement is supposed to help support healthy memory. It's said to do this by helping helping to detoxify the brain, by using natural ingredients. This is supposed to help the brain to work better.
CeraPlex vs. SeroPlex
SeroPlex is a prescription SSRI antidepressant medication. CeraPlex is a dietary supplement. SeroPlex and Ceraplex are not the same thing. Given the similarity in their names, I wonder if this was just a coincidence? Could this similarity have played a role in the company changing the name to Procera Protect? This is unknown. Just know that Seroplex (the drug) has no connection to Ceraplex (the supplement).
Who Makes Procera Protect (Ceraplex)?
Ceraplex is a product of Key View Labs. They also sell the memory supplement, Procera AVH. The company is located at 5737 Benjamin Center Dr Tampa, FL 33634-5293. The company website is ProceraHealth.com. As, the name suggests Procera is the flagship product of this company.
For much more on the see the Procera AVH review.
Procera Protect Research
No research could be located to support the Ceraplex supplement. So, to figure this supplement out, we need to look at its ingredients. Lets do that next.
Procera Protect Ingredients
Since I first reviewed this supplement, not only has the name changed (from Ceraplex to Procera Protect), but some of the ingredients have changed too.
Two capsules contains the following ingredients:
|Amount Per Serving||Percent Daily Value|
|Vitamin B12||667 mcg||11,117% DV|
|Procera Protect Blend consisting of||720 mg||n/a|
|Alpha lipoic acid||n/a|
|Japinese knotweed extract||n/a|
In the table above “NA” means no daily value established.
Let's look at each of these ingredients closer
Procera Protect provides a LOT of vitamin B12 – over 11,000 % of what its thought we need to stay healthy. The type of B12 used is methylcobalamin.While they dont say why the supplement contains so much, possible reasons include
- B12 helps lower homocysteine, a compound related to heart disease
- older folks may not absorb B12 very well
- Older folks may be deficient in B12
- Some speculate B12 may be related to depression
- Some medications -like diabetes meds – lower B12 levels
Or it could be because B12 is a sexy vitamin, with hopes it may improve energy levels? If your not deficient, it won't do this. All that said, one study from 2011 did not show that methylcobalamin reduced dementia symptoms in older adults with dementia.
Likewise another study also noted no significant effect of vitamins B12, B6 or folic acid in people with mild to moderate Alzheimer's disease.
Homocysteine appears to play a role in heart disease – and this is related to poor brain health.If that is the reason then, I'd wish they would have added folate to the supplement. Folate (folic acid) also lowers homocysteine and I'd bet many older adults lack this vitamin due to poor eating habits.
Side note. Does Vitamin B12 help weight loss? Read my review.
N-Acetyl-Cyesteine helps us make a very powerful antioxidant called glutathione. It also appears to reduce levels of homocysteine, a compound, described above, which seems to play a role in heart disease. NAC might also be able to get into the brain too which again points to its brain health properties.
One review noted NAC might help Alzheimer's disease and autism too. More research is needed though to understand this better.
Alpha Lipoic Acid
This is an antioxidant compound. When used long term, alpha lipoic acid seems to help some people who have Alzheimer's disease according to a very small study (43 people) who were given 600 mg / day for 2 years. That said, an earlier review of alpha lipoic acid and dementia research found no good proof that it worked in light of the lack of quality research.
Likewise a study lasting 16 weeks also didn't show it helped Alzheimer. The amount used in this study was 900 mg per day.
The extract of turmeric used is curcumin. Both tumeric and curcumin have anti-inflammatory qualities. Procera Protect uses a specific, patented curcumin called BCM-95. Research suggests curcumin may help depression But, At least one preliminary study noted 6 months of curcumin use did not help Alzheimer's disease . For what it's worth, Research shows that regular exercise reduces inflammation in the brain.
Turmeric/ curcumin is a fine supplement that seems to do many things. But when it comes to helping dementia, more research is needed.
Quercetin is an antioxidant and found in red wine as well as several foods. In one study, researchers speculated quercetin might protect brain cells. Other research finds quercetin can lower blood pressure in humans. A mouse study suggested it may help modify Alzheimer's disease.
Reducing blood pressure would lead to less stress on blood vessels, which might reduce blood vessel damage in the brain and elsewhere. This might play a role in reducing or delaying dementia symptoms.
Obviously, the effects of quercetin are likely to be much more complicated than this. To achieve this blood pressuring effect, about 700 mg of quercetin per day has been used. That is more than is in Procera Protect.
Japanese Knotweed Extract
The extract used is resveratrol. Resveratrol is the classic anti-aging supplement. Like a lot of the other ingredients in Procera Protect, resveratrol is an antioxidant. Another name for Japanese knotweed is Polygonum Cuspidatum.
Resveratrol reduces blood vessel aging by reducing free radical damage. That’s good. Other research suggests resveratrol helps clear the plaques —that clog up nerve pathways —that are characteristic of Alzheimer's disease. That's good too.
Procera Protect Side Effects
In healthy people I think Procera Protect is safe. For those who may not be healthy, here are some things to think about. This list is not complete:
- If you take any blood thinner medications, speak to your doctor and pharmacist. Some of the ingredients in this supplement may interact with blood thinner meds.
- Speak to your doctor if you take ANY medications such as those for heart disease, high blood pressure, low blood pressure, diabetes or thyroid problems.
- Stop taking Procera Protect at least 2 weeks before having surgery.
- Consult your doctor if you are pregnant/breastfeeding.
- If you have any health issues, speak to your doctor first.
Ceraplex Vs. Procera AVH
The ingredients in Procera Protect are very different than Procera AVH. Also, both supplements are supposed to work differently. Procera Protect is touted to be a broad spectrum antioxidant. There is no evidence either way that Procera Protect (Ceraplex) and Procera AVH work better together. That would take research to know for sure. Procera AVH does have a small study on its benefits while Ceraplex does not.
See the Procera AVH review for much more info.
Buy Procera Protect
Ceraplex can be obtained directly from the company or at local stores like vitamin shoppe, GNC, CVS, Walgreen and Rite Aid.
Procera Protect Cost
The product website had the cost at $29.95. This is actually a lot less than when I originally reviewed this supplement (back then, it was 59.95 plus shipping and handling).
Does Procera Protect Work?
Without studies, it's difficult to know if Procera Protect (Ceraplex) works or not. When it comes to a general antioxidant supplement, the ingredients in the supplement seem logical but that doesn't mean people with memory problems will notice a difference. For people who don't have memory problems and looking to reduce their chances of getting dementia, there is much more evidence for regular exercise than this supplement. Something to think about.
What Do You Think?