Update 2/11/20. MeraTrim is a weight loss supplement that I've started to notice showing up as an ingredient in diet products lately and this has generated some questions about what it was and if it worked or not. So, in this review, I want to look at the research on MeraTrim and see if I can help people make sense of it. MeraTrim is not only found as an ingredient in diet supplements it can also be an ingredient in some weight loss supplements. So does it work? Does it have any side effects? Let's look at the research.
What Is MeraTrim?
MeraTrim is a weight loss supplement that is composed of 2 ingredients:
- Sphaeranthus indicus
- Garcinia mangostana
Let's briefly look at each ingredient and then review the weight loss evidence.
This is another name for mangosteen. Garcinia mangostana is not the same thing as garcinia Cambogia. Here's my review of garcinia Cambogia for more information on that supplement. I looked at mangosteen when I reviewed the health drink called Vemma.
This ingredient is sometimes called East Indian Globe Thistle. It is not the same thing as milk thistle. While I saw no weight loss research for this herb, I did find some preliminary evidence it might reduce blood sugar in rats.
Even though individually, they may lack weight loss evidence in humans, MeraTrim itself does have some human clinical trials. Let's take a look at that evidence next.
There are three clinical research on this weight loss supplement. There is some research on Meratrim. They are summarized below. The first two studies were supported by a grant from InterHealth Nutraceuticals, the maker of MeraTrim. That said, the researchers report no conflicts of interest (that's good).
In this investigation, 60 overweight people were randomly given either a placebo or 400 mg of MeraTrim twice a day ( 800 mg total per day) for 8 weeks.
Results. Researchers noted that those getting Metatrim lost an average of 8.2 pounds (3.74 kg) and 2.1 inches from their waists (5.44 cm). Those getting MeraTrim also saw an increase in adiponectin, a hormone made inside fat cells that are involved in fat burning and regulating blood sugar levels.
Remember, The people in this study ate only 2000 calories per day and were instructed to walk 30 minutes per day, 5 days per week (150 minutes per week). In other words, they likely ate fewer calories and did some type of exercise.
This investigation has the same title as the study above and was conducted by the same group of researchers. One difference is that in this study 100 people were used. This study also lasted for 8 weeks. People were randomly given either a placebo or 400 mg of MeraTrim twice a day (800 mg total per day).
Both groups were given meals that equaled 2000 calories per day and they were also instructed to walk 30 minutes per day, 5 days per week (150 minutes per week).
Results. This study also noted MeraTrim promoted weight loss than those taking the placebo. Those getting MeraTrim lost about 8 pounds (3.8 kg). The weight loss started after two weeks.
Problem. When reading this study, it looks like the results from the first study (study #1 ) were combined (pooled) with the results of this investigation.
Honestly, I would prefer they reported the results of the studies separately. While both investigations were similar, how do we know the results from one study didn't influence the outcomes of the other study?
This investigation involved 50 people who were given either 800 mg of Meratrim a day or a placebo. The study lasted 16 weeks. Those who received Meratrim lost more weight than those who took a placebo. Like the first two studies, those in this invesgigation also consumed only 2000 calories per day and walked 30 minutes a day, 5 days a week. Still, those taking the placebo did this too and yet the Meratrim group still lost more weight.
MeraTrim And Dr. Oz
If you research MeraTrim you may see references to it appearing on the Dr. Oz Show. The Dr. Oz website has removed the video segment featuring Meratrim – as well as many other supplements featured in the past. I believe this was due tough questions Senator McCaskill had about supplements appearing on The Dr. Oz Show. Here is the McCaskill video.
Here's a video of when the supplement was featured on QVC
How Much Of Each?
Because MeraTrim is made of two different ingredients, some might wonder if they could just take those two ingredients individually and get the same weight loss effect – for less money. I'd imagine that it is possible, but one sticking point is how much of each ingredient does MeraTrim contain?
The research doesn't specifically tell us how much of each ingredient is present although MeraTrim does a 3 to 1 ratio of ingredients.
In other words, there are 3 times more Sphaeranthus indicus than Garcinia mangostana. If each dose contained 400 mg total, then 300 mg should be Sphaeranthus indicus and 100 mg should be Garcinia mangostana.
MeraTrim Side Effects
The research shows significant side effects of MeraTrim. That said, here are a few things that are worth mentioning. This list is not complete.
- Start with the least amount possible for the first week, just to see how you respond.
- Both human studies used 800 mg of MeraTrim per day for 8 weeks. Until more is known, don't use more than 800 mg per day until we know more.
- The ingredients in MeraTrim might have a blood-thinning effect. This could be an issue for people taking blood thinner medications.
- Speak to your doctor before using Meratrim if you are pregnant or breastfeeding.
- Stop all supplements at least 2 weeks before surgery.
Keep in mind that supplements with multiple ingredients may have additional precautions. When in doubt, show the list of supplement ingredients to your pharmacist and doctor for more specific recommendations.
What Is The Best Brand?
MeraTrim is a product of InterHealth Nutraceuticals (InterHealthUSA.com). All supplements that contain “MeraTrim” get it from this company. The human clinical studies suggest an effective dosage at 400-800 mg of MeraTrim per day. If MeraTrim is going to work (promote weight loss), the effects might be seen after 2 just weeks.
Does MeraTrim Work?
While the research suggests Maratrim may help people lose weight, I'd like to see a couple of other studies to know for sure. Also remember, if its really going to work, it should be combined with eating fewer calories and exercise. That's what happened in the clinical studies.