Leptigen is a weight loss supplement that I first learned about via someone who left a comment on one of my other reviews. I became interested in it because it contained an ingredient called MeraTrim that I've wanted to investigate for a while. Does Leptigen work? Does It have any side effects? Who makes Leptigen? These will be some of the questions I'll try to answer in this review. Leptigen is not the same thing as Lipothin which is another weight loss supplement. I wanted to mention that since they both sound alike. See the DietSpotLight Burn review for more information.
What Does The Name Mean?
The name Leptigen is interesting because it reminds me of “Leptin” a hormone, made inside fat cells that plays a role in hunger. My guess is this factored into the naming the supplement. The idea subtly being that leptigen might somehow influence leptin levels and in doing, curb appetite and promote weight loss.
That's my guess anyway. Take it for what it's worth.
That said, I'm not aware of any evidence that Leptigen alters leptin levels.
On the FAQ page of Leptigen.com it's stated that:
“we referenced 284 published scientific studies to verify the claims that we make about the ingredients in Leptigen.”
While I do know that research exists on the ingredients of the product, that is not the same thing as research on Leptigen itself.
Just to double check, I searched PubMed.gov for “Leptigen.” No relevant studies showed up.
- I then searched ClinicalTrials.gov and also saw no research studies.
- I also googled “Leptigen Research.” While I saw other websites discussing the product, I saw no clinical research.
Therefore, I'm forced to conclude at this time that Leptigen has no published, peer reviewed evidence. Of course, that doesn't mean it doesn't work. Let's now look at some of the research on it's ingredients.
According to Leptigen.com, each capsule of Leptigen has these ingredients:
|Decaffeinated green tea extract||200 mg|
|Chromium polynicotinate (Chromate)||100 mcg (83% DV)|
The label of Leptigen that is on the product website does not state the amounts of some ingredients. That is why you see “amount not given” in the table above.
The label also lists these 2 ingredients as well:
- Green Select EGCG
I'll cover these ingredients in the Research Section below.
Leptigen also contains these “other ingredients” :
- Silicon dioxide
- Magnesium stereate (vegetable source)
- Lecithin phospholipids
I don't feel these other ingredients play a role in any weight loss effects of this supplement. As such, I won't cover them in my review.
This is another name for chromium. It's a combination of chromium and niacin (a B vitamin). Supplements often contain chromium bonded to vitamins to increase absorption. Chromium has been used in weight loss supplements for many years, although I am hard pressed to find good evidence it works. Here is my review of chromium and weight loss if you want to see the research yourself.
Chromium polynicotinate is sometimes found in some weight loss supplements and this is likely due to a study from the 1990s noting that it helped women lose weight (woman who got chromium picolinate actually gained weight). Here's my review of chromium polynicotinate for more information.
Leptigen uses a trademarked brand of chromium polynicotinate called “ChromeMate” made by a company called InterHealth Nutraceuticals (InterHealthUSA.com). To support it's effects, I found this 1999 study noting it helped dieters lose weight more than a placebo.
There is also this 1997 study that also showed chromium polynicotinate helped.
Leptigen contains 100 micrograms of ChromeMate which is more than both of the above studies used, so that is good. That said, I'm still on the fence when it comes to this ingredient helping weight loss. I'd like to see a couple more studies.
ChromeMate is on Amazon for those wanting to see what others have to say
Many weight loss supplements contain caffeine. I think the idea here is twofold:
1. caffeine appears to have a small fat burning effect
2. people who are more awake might burn more calories through doing more physical activity
Leptigen has 75 mg of caffeine per capsule. That's about what is in a cup of coffee.
Green Select EGCG
This is a trademarked version of green tea found in Leptigen. This form is supposed to be better absorbed than “regular” green tea. Another name for this ingredient is Green Select Phytosome. I found one study showing Green Select Phytosome helped people lose weight. I review that study in greater detail in my review of SlimQuick so see that for further details. I could not tell how much Green Select EGCG is in Leptigen.
MeraTrim is another ingredient in Leptigen. It's composed of two separate ingredients:
- Sphaeranthus indicus
- Garcinia mangostana
There is some weight loss research on MeraTrim. I found 2 studies and both said it worked.
The research notes that Meratrim works when people take 800 mg per day (two separate doses of 400 mg). I'll assume Leptigen has this amount but I'm not sure as I could not determine the amount from the label.
Here is my MeraTrim review for more insights on this ingredient.
Who Makes Leptigen?
According to Whois.com, a site that gives information about other websites, the Leptigen.com website was created in 2015.
I called the customer support number for Leptigen.com who told me that the name of the company that makes the product is called Green Bracket LLC. According to the Better Business Bureau, they are located at: 4135 Laguna St, Coral Gables, FL 33146-1442.
Interestingly, this address corresponds to another company called “Triton Web Properties.” This is a company that develops, owns and operates websites. Their website is Tritoncorp.com.
Their customer support person also told me that Leptigen is made at a facility in California. The Better Business Bureau gives Green Bracket LLC a rating of “B+” at the time I wrote this review. See the BBB file for updates and more information.
Interestingly, when I wrote this review, the website listed at the BBB for Green Bracket LLC is “Avesil.com.” Before Leptigen, there was another weight loss supplement called Avesil. Their ingredients look very much alike. Here's the thing, According to The Better Business Bureau, Avesil is an alternate business name for Green Bracket LLC / Triton Web Properties.
Update: Another name for the company is DietSpotlight.com – a website that provides reviews of dietary supplements. The founder of DietSpotlight.com is the same person who founded Triton Web Properties and Green Bracket LLC.
Leptigen and Avesil have both been promoted on DietSpotlight website. This website now has another supplement that they are marketing,
called DietSpotlight Burn.
How are they all different from each other?
How To Contact Leptigen
The BBB lists this contact number for Green Bracket LLC 800-555-3951. This is the same number listed on the Leptigen.com website. This is the same contact # is DietSpotlight, the website that makes and markets Leptigen.
In Australia, call: 1800-112-947
In the UK, call: 0800-148-8251
Does Leptigen Contain Soy?
Yes, the label indicates that the product contains soy. My guess is that this soy comes from the Green Select EGCG extract which has a little bit of soy.
How To Return Leptigen
The supplement comes with a 120 day money back guarantee. Before returning Leptigen call their customer service department at 800-555-3951. You need to get a return merchandise number (RMA number) and this needs to accompany anything that is returned. the product website says people have 120 days -from the time they order leptigen – to return it.
To get a refund, they also say you have to include a copy of your sales receipt too (or a note with your order number, name address email address phone number) and a reason why you are returning it.
The FAQ page of Leptigen.com also lists this address for returns:
4135 Laguna St.
Coral Gables, FL 33146
I recommend you call the company first before sending it back. Their number is: 800-555-3951.
Oddly, I noticed the product return page stated “We cannot accept returns on overly used products.” I don't know what “overly used products” means. Does it mean, they won't accept returns on empty bottles? what if you used only half of the bottle? This is a vague statement.
Also interestingly, when I googled their return address, I noticed it was the same address as a company called Triton Web Properties (TritonCorp.com). This is a company that owns and operates other websites. Its other names include DietSpotlight.com and
How Much Does It Cost?
When I wrote this review the product was about $110 for a bottle containing 60 capsules. That is a LOT of money to pay for a supplement that has never been tested clinically.
Update, the product website now has 3 options for buying
- Option 1: “Best Value.” $89.95 for a 90 day supply plus 5 free gifts.
- Option 2: “Most Popular.” $99.95 for a 60 day supply plus 5 free gifts.
- Option 3: ” Getting Started.” $109.95 plus 5 free gifts.
When I called to ask what the free gifts were, I was told the gifts consisted of:
- A meal planner
- Capsule carrier
- Cheat sheet
- Tape measure
I was also told that they are retiring this supplement and replacing it with DietSpotlight Burn. So if you call to order Leptigen, that is the supplement you will be getting. No worries though because Leptigen and DietSpotlight Burn are the same thing.
Remember the Meratrim ingredient is likely the main active ingredient. Meratrim costs much less.
Leptigen Side Effects
I'm not aware of any side effects from Leptigen when this review was created. Searching for “leptigen side effects” turned up nothing when I looked. Looking over the ingredients, I think in healthy people, Leptigen is probably safe. That said, here are some things I believe are worth mentioning. Speak to your doctor if you think any of this pertains to you.
- Stop taking the product – and other supplements – at least 2 weeks before surgery
- Don't take the product if you are pregnant or breastfeeding
- Speak to your primary care doctor if you have liver problems, heart problems, thyroid issues, have had a stroke/ blood pressure problems or are diabetic, have depression, emotional/psychiatric issues.
- Don't take Leptigen close to bed time due to its caffeine content.
- If you take any medications, show the ingredients to your doctor/pharmacist first.
This list is not complete so if you feel you are not completely “healthy,” I think it's wise to show the ingredients to your doctor/pharmacist to get more specific recommendations for you.
Does Leptigen Work?
For me, it's always about the research when it comes to whether something works or not. Since I can't find any proof for Leptigen- itself – I can't say either way. If it worked for you, great, let me know. I'm curious. That said, there are some interesting studies on some of its ingredients, namely MeraTrim and Green Select Phytosome.
If Leptigen is going to work, I believe those are the main active ingredients and of those, I think MeraTrim might be the main active ingredient. If I'm right, then this is good news because MeraTrim costs less than Leptigen. If it's going to work, you should know in about 2 weeks if the Meratrim research is correct.
Here's MeraTrim on Amazon if you want to see what others are saying.