Update 3/17/21. When I first heard the name Syntheroid I thought it was a supplement for the thyroid because its name sounds a LOT like the drug synthroid that people take for hypothyroidism. But Syntheroid is billed as a natural testosterone booster whose motto is “power, mass, sexual performance.” The makers of Syntheroid claim that it can improve speed, agility, and reaction time, as well as muscle size and strength. This is in addition to the claim that Syntheroid can maintain libido during hardcore dieting. These are all pretty bold statements so I'm not surprised if people wonder if Syntheroid really works or not? Let's now review Syntheriod and what can be discovered. Also see my review of the HGH supplement, SeroVital.
Who Makes Syntheroid?
When I checked the product website – syntheroid.com -I couldn't find out who makes this product. It's only after some digging that I discovered that syntheroid is made by a company called XPI (xpisupplements.com).
The address of XPI labs is 965 N 1430 W Orem, UT 84097. The link provided is to show what the area looks like. I see a lot of warehouses. I did not see any building called “XPI laboratories” but since most of the buildings appeared dull looking – built for function, rather than looks – I'm sure it's in there somewhere. XPI labs do not seem to have a BBB listing when I checked on 12/7/11.
On the Syntheroid.com website, there is a video of a 31-year-old man named Josh Dahl (“The Josh Dahl Story”) where he says that Syntheroid makes him feel like he's 21 years old again. They listed his name like we should know who Josh Dahl was – which I didn't – so I did some goggling on who Josh Dahl, was but could not find anything. Maybe Syntheroid did do what Josh said but in general, I take all testimonials from people I do not know with a big grain of salt.
Syntheroid Ingredients
Kudos to the Syntheroid website because they do tell us what's in this product. If you take 3 capsules of Syntheroid -the recommended dose – you get the following:
| Tribulus Terrestris | 650 mg |
| Testofen | 300 mg |
| Aminogen | 250 mg |
| Coleus forskohlii | 125 mg |
| Milk Thistle | 120 mg |
| Alpha lipoic acid | 100 mg |
| Eurycoma Longifolia | 100 mg |
| Horny goat weed | 100 mg |
| Bioperine | 15 mg |
Remember, even though the name syntheroid sounds like a drug, syntheroid is not a hormone or a pro hormone. It's a dietary supplement. They even say this on the Syntheroid website.
Looking over this list of ingredients, Syntheroid has some things found in many other products I've reviewed in the past.
For example, Syntheroid has Tribulus. I know people have said that tribulus works for them but I have been skeptical about the claims of this herb since the 1990s when it first started getting popular. For more on this, read the Tribulus review.
Despite the hype about Tribulus and testosterone, I can't find any proof that it works. For example, in a study published in 2001, Tribulus didn't work. In another study from 2007 tribulus didn't work.
If anybody knows of a“tribulus raises testosterone study”, please let me know and I will happily update my reviews on this herb.
Now, no study is perfect, so if you really want to know if tribulus raises testosterone, get your doctor to check your testosterone before starting tribulus (or Syntheroid) and after a month of using it. This is the only way you can know for sure if it worked or not.
As for Testofen, it's a cool-sounding name and was likely invented to give the impression that it raises testosterone – but it doesn't. Testofen is just a made-up name for the herb Fenugreek. For more on fenugreek- testosterone research also see the review of Ageless Male.
Fenugreek might raise insulin levels. Since insulin helps us use amino acids, that means it has a mild anabolic effect. I'm guessing this is why it's in a testosterone booster supplement. Here is Fenugreek on Amazon.
Ironically, this effect on insulin is why fenugreek is also found in diabetes supplements. For example, the diabetes supplement Glucotor V2 also has fenugreek. In fact, this diabetes supplement has the same amount of fenugreek – 300 mg – as Syntheroid does.
Aminogen
The Syntheroid website says that Aminogen is a ” proprietary proteolytic synthetic enzyme” that “was created to improve protein digestion and absorption.” That means at that Aminogen is not an amino acid supplement but rather just a fancy name for a protein-digesting enzyme supplement.
Unless you have a problem absorbing protein you don't need enzyme supplements. They say that Aminogen “works to produce a higher bioavailability within your body, particularly to your muscles.” So, where is the proof of this? As far as I can tell neither Aminogen – or Syntheoid – has any peer-reviewed clinical proof that it does anything. Since they can't prove to me that this statement is true, I discount it.
Just a heads-up, animal protein – has a very high absorbability, so unless your doctor has told you that you have a problem with digestion, you don't need any supplemental digestive enzymes. What's a good way to remember animal protein? It's any food that had a mother. That's how I remember it!
Coleus Forskohlii
This herb is said to be a metabolism booster and weight loss supplement. The idea here is that coleus forskohlii (forskolin) stimulates fat-burning enzymes that help us lose weight. One small study of older, overweight men also noted that coleus forskohlii increased testosterone levels.
This is the logic why Coleus forskohlii is found in many weight loss products such as Lean and Fab and Apidexin to name a few.
Here is coleus forskohlii on Amazon.
The problem with coleus forskohlii research is that they often have problems and so for the moment, I will keep an open mind about forskolin until better research is done. For more on this research, read my Coleus forskohlii review.
Milk Thistle
Since steroid abuse is thought to damage the liver, and since Syntheriod is reputed to be a testosterone booster, I'm guessing this is why they added the liver-protecting supplement -milk thistle – to Syntheriod.
That is the most obvious answer I can guess because there seems to be no clinical proof that milk thistle raises testosterone or improves libido. There is interest in milk thistle for diabetes because it has been shown to reduce blood sugar levels.
Might stabilizing blood sugar levels help people have better workouts? In theory, maybe. This might be another reason for putting milk thistle in Syntheroid.
Mostly this herb is an antioxidant and one of its active ingredients is a compound called Silymarin. Syntheroid has 120 mg of milk thistle but I can't tell from the product website how much Silymarin this translates into.
Alpha Lipoic Acid
Like milk thistle, alpha-lipoic acid has also been researched for its blood sugar-lowering effects. I've seen this stuff used in many exercises and weight loss supplements despite any good proof it helps weight loss or exercise.
For example, alpha-lipoic acid is also found in the bodybuilding supplement Stemulite and Jillian Michaels Fat Burner as well as the Plexus Slim weight loss supplement.
Like several other ingredients in Syntheroid, eurycoma longifolia is found in a variety of other products. For example, this herb is one of the main ingredients in TriVerex – a male enhancement product you may have seen on late-night TV.
It's probably eurycoma longfolia – as well as horny goat weed – that is at the heart of the claims that Syntheroid improves sex. I don't want to reinvent the wheel on these ingredients, so please read my words on TriVerex” for more info on the research behind both Eurycoma longfolia and horny goat weed.
The same thing goes for Bioperine. For more on this ingredient see my Lean and Fab review.
Syntheroid Side Effects
I think if you are healthy you might not notice any side effects with Syntheroid. If you are not “healthy” or take any medications, see your doctor first. Syntheroid is probably very safe in healthy people but as far as I can tell this assumption has never been tested. Here is Synteroid on Amazon for those who want to check out the comments from others who have used it.
One older study noted that alpha lipoic acid might lower thyroid hormone levels. If this holds true, it might also reduce vitamin D levels as well as metabolic rate. I'm not sure if this “side effect” is true or not but it's worth mentioning just in case you have hypothyroidism. Alpha-lipoic acid might also add to the effects of insulin and other diabetes drugs.
Fenugreek might cause hypoglycemia (low blood sugar) and interact with insulin or other blood sugar-lowering medications. It might have an even greater blood sugar lowering effect when combined with alpha-lipoic acid.
Milk thistle might interact with many medications like coumadin (a blood thinner). The herb might also have an estrogen effect that might be bad for women with a history of breast cancer. This effect is probably a long shot, but speak to your doctor if you are not “healthy” just to be safe.
How Much Does Syntheroid Cost?
They say 1 bottle currently costs $59.95 on the Syntheroid website. I think that is a lot of money for a product that has zero clinical proof that it works.
Here is Synteroid on Amazon to compare prices.
Does Syntheroid Work?
On the XPI labs website, they say that Syntheroid “was scientifically formulated to boost testosterone levels, improve protein synthesis, absorb nutrients, and burn fat faster than any other legal supplement on the market.” Scientifically formulated? How did they scientifically formulate this product but did not conduct any scientific tests to prove Syntheroid actually does what they say?
In my book, you can't invoke the name of the mighty god science (lowercase g) without doing actual scientific testing – in humans. Failure to do so is just bad science. They also say that with Syntheroid, you can boost testosterone by up to 400% but proof of this cannot be located.
If you are interested here is Synteroid on Amazon.
The body rush is a pre workout supplement it gave me endless amounts of energy on the treadmill. I actually had to stop myself at 3 miles. i didn’t know if it was safe to keep going because it didn’t hurt at all and i usually only run a mile after my work out and it killed me.
Syntheroid was horrible it didn’t do anything at all. Big waste of money. If any one is thinking of getting it dont unless you wanna waste $60. Took it with a good work out schedule and didn’t notice any extra improvement that i wouldn’t normally notice without it. What i did notice is a little sexual appetite increase. Thanks for your help Joe. I started this supplement called force factor body rush and it is awesome have you done any work on it?
Rich, I did review “Force Factor” but have not heard of force factor body rush
http://supplementclarity.com/force-factor-the-facts-you-need-to-know/
hi joe am glad i found your page about to use this product probaly next month i let you know if work i haven’t been in the gym for 1 year again a few pound so let give the tried to see
I have recently tried this product. I’ve never tired a test booster before and had a friend suggest this one, so I order it. I didn’t notice much at first but after 10 days or so I really notice a change in libido. I would be driving down the road and get and erection like i was eighteen or something. Now I’m not saying that this product made me feel like I was eighteen. In fact other then the erections and bigger libido I didn’t notice a difference. Same strength, no weight loss or any other noticeable effects. So if your into random erections this product fits the bill. I just found your wed site and it is great.
Thank You for running a service actually needed on the net.
Tommy, thanks for the feedback and I’m glad you found my website too 🙂
Hi Joe,
2nd try…as I made a typo on my email address.
I just discovered your site…and I like it too, as you blog and review supplements, and try to help people from getting fooled into buying supplements through hype colloqialiisms that might tend to stray us into thinking are ‘truths’. However, there is just something I’d like to point out, (a constructive criticism, if I may, or perhaps you could correct me if I am wrong)…you say that you do research on on people that make certain claims, and you do research on what has been researched, but you don’t say where you went exactly to say what you are saying.
Do you have or keep a record somewhere of who said what and where? Does all your research come from the internet or other sources like books, medical journals, health articles etc…? How extensive is your research? The reason why I ask, is because, even though you don’t like hype, when I read other peoples comments about your blog…they are hyping about you and your comments, which could also lead people to believe things that may or may not really be true either.
I dunno…just something I’m feeling, and thought I’d express it…feel free to respond…would love to hear how you might respond to it.
Thanks for your efforts by the way. Your blog does seem to stand out in some way apart from the rest.
Regards,
Vic
Vic, great question! When I say I research a product etc. I do various things. I first look at their website to see what the product is about and the claims being made and how they sync with what I know. If I can, I also try to find info on the company via the better business bureau website. Mostly though I look at the published research on either the product or the ingredients in the product. I try to look at as much of the research as I can find and see if I can find a consensus (it works or it doesn’t work, what the side effects might be etc). If I can, I also try to find problems with the research in the hopes that other researchers might see my words and try to duplicate the study to make it better.
Since I can’t do any actual scientific tests myself here (I wish!) most – probalby 95% – of the links you see on in my reviews are are to the research studies themselves. Most of that research can be found in the national library of medicine. I believe people should be able to see the research for themselves and that’s why I link to them. That way people dont have to take my word for it. I try to be as transparent as possible. I only consider research studies that have gone through the peer review process or come from sources that I trust.
I’ve got quite a few books on supplements, nutrition, biochemistry etc here and so I consult those as well. I dont have a record of who said what but sometimes I remember things if they are said often enough. For example, this is what happened when I saw TV commercials for the Herpes Cure Report http://supplementclarity.com/herpes-cure-report-kevin-trudeau/
Where there is no proof one way or the other for a supplement doing something, I try to mention this or if I can, try to explain how something might -or might not – happen based on what is currently known. My hope here is that I’m able to give people questions to take to their doctor who then might be able to explain things better than I can.
So basically I just try to let the research speak for itself.
If you can think of any other ways that I can improve let me know and I’ll see what I can do. 🙂
Hey lawerence please keep us up dated about your progress. thanks
I have just had a Dr. order a blood test taken for T -levels. I am 47 and looking into a few health concerns. I am researching different supplements for boosting my testosterone. I have used BioEntopic cream in the past. I am looking for an alternative, natural booster.
Lawrence congrats on getting your T levels tested! If you find anything that raises it let me know. Good luck with your other health issues also.
I started synthroid today from my first time I didn’t get my testosterone levels checked though. I haven’t seen anyone else is with lies about their results from synthroid besides the female and the one guy whos hair is growing fast. Has anyone else got back to you? If so what did they say? I will keep you updated on my progress with synthroid, if any.
Rich, so far nobody has gotten back to me other than what you see in the comments. I added the word you forgot about 😉
This is off topic, but I was wondering about the HGH supliments, I researched the web and didn’t find anything, bunch of reviews that I suspect were ads. The HGH thing makes sense if the whole putuitary gland thing is true, just don’t know what to believe anymore.
I’m 42 and worked out my entire life on and off, played football and wrestled in HS. I don’t know if its in my head or if its my age, but when I’m at the gym I just can’t push like I used to, am I slowing down? Should I try a T-booster or an HGH Sub. Also would buying from a place like GNC be safer, the web stuff is cheaper, but seems so shady. Anybody who used/uses these type of Sub. I would like to hear you input
Carl, I likewise would trust a GNC before a company that I have not heard of before. That said get your HGH levels checked before you try any product and again after a month. I dont think any product will raise your HGH levels but the only way to know for sure is to check your levels before and after trying a product.
There are some interesting points of view on this product. Some more passionate than others. I’ve just started it myself and I am skeptical. I bought 3 bottles so my skeptism is warrented at those prices. I’m expecting results. From effects, I’ve found that I sweat more profusely (sp) during my work-outs. My hair, which grew fast before, now seems to grow much faster. So, there does seem to be some kind of an affect.
Having just been on it 3 days I don’t quite feel 21 again ;o). I’ll keep you posted. Another side-effect I did notice is I’m pee’ing a lot more during the night. Not sure if this is a good thing? I don’t recall pee’ing this much when I was 21 LOL. I plan to run out this supply as directed. I’ve upped the intensity of my work out to gauge impact. I’ll post results and/or milestones as they occur.
Lol, I just read Michael’s comment on this product and I feel like anyone with some sort of familiarity with science and the scientific method would know that there is something called the placebo effect. In order to truly test a product you must be able to distinguish the difference between what is in your mind and what is actually happening! Now, if in your mind you think this product is going to work then it will automatically motivate you to work out harder which will lead to results regardless if you were taking the supplement or not!
Thank you please come again….
First of all, after receiving my bottle of Syntheroid from syntheroid.com, I looked inside and it didn’t look like there were 90 capsules, so I poured the whole bottle out and sure enough there were only 89 capsules. Okay, so I’m missing one pill which at $60 for 90 translates to about 67 cents per pill, which is a meager amount but still unexpected considering they advertise such excellent manufacturing practices.
Secondly, the web-site advertises one bottle as being a one month supply and yet on the bottle it says to take 3 capsules 2-3 times daily…how does this translate to a one month supply?! So anyway, I’ve been taking 3 capsules 3 times daily, and after 10 days of use I’ve completely exhausted my supply.
I didn’t really notice any change in my physique nor did I notice any accelerated recovery from my workouts. The only reason I decided to purchase this product was because they offer a 100% money-back guarantee on their web-site….After using their product I think I want my money back. Totally not worth the $6 a day (3 capsules 3 times a day), I think I will just stick with my creatine supplements which actually do work!
Erik, do let me know if you had any trouble getting your money back.
Joe,
Are there any test boosters you would recommend?
Vince, not until I see proof that they actually do raise testosterone in people. That’s why I recommend that people get testosterone checked first and after a month of using a product. That is the only way to know for sure its doing something.
Anyone trying Syntheroid that wants to share results, Bach, did you receive your new order? Joe; can you recommend a pre-workout, pre-comp energy boost without the banned substances for a master’s sprinter? Thanks!
Gary, Id say keep it simple and have some light carbs/protein a few hours before the sprint. maybe some caffeine might help too.
Hi Joe, just came back to look at your site and saw all these comments, what a whirlwind Michael was huh!
I liked the stuff myself, made me feel good and like i wanted to be active and really, that’s all i wanted. If i want to be active I’m gonna gain muscle anyway.
I’m gonna order it again – gotta get it from the US to Australia and I’m due for a check up anyway so I’ll get my T levels checked.
Can’t wait to feel productive again.
Remember how i was saying my sleep was pretty bad when i stopped taking it, i was wondering if it effects malatonin levels… just food for thought.
Bach, yeah I guess I really made him mad! I’m glad its helped you and I’m not sure about the connection to melatonin. since it was bad after you stopped, my first thought is some sort of withdrawal symptoms but Im just shooting from the hip on that. hopefully you got your sleep back on track before too long passed. Yes I’ll look forward to hearing about your T levels thanks!
Please note;
Orem, Utah. is a hotbed of companies that sell items online.
I have found very few are honest, and any “That you may do business with should be checked out thoughly.
Good day everyone,
Well, I must say, I think I’m suffering from analysis paralysis. Or, I’ve researched this subject of testosterone supplementing to the extent I don’t know which way is up and what’s true or which is B.S.
I’m 39 and have been taking notice of all the low T ads and wanted to begin taking a supplement to hopefully get a “boost” to help me shed some unwanted pounds and get some of my old strength back, as well as maybe acquiring some mass.
I’m somewhat active, I play hockey in a men’s league, workout 3-4x’s a week (okay, sometimes 2x… Haha) But, I plan to hit the gym harder once I find what I want to try. I trained and ran a half-marathon last summer and did well considering I’ve never ran before, unless I was being chased by a dog…. 🙂
I was looking into Syntheroid, Neogenix’s “Supremacy” and a few others. I hate to just roll the dice with something that cost’s 60 bucks a month, so I’m looking to make the best choice I can possibly make.
So, I guess my question/comment is, based on ingredient purity and “possible” effects, is Syntheroid the “best” one to try out? I’ll be right back, I need to go grab a couple aspirin. LOL
Thanks for your time.
Kenneth
Kenneth, have you had your testosterone levels checked to see if you are low? I think that is the first step. As I’ve said I’m skeptical of T booster supplements but even if I am wrong, I think knowing your T levels now will help you not only compare what effect any testosterone booster might have, but it will also help doctors help you better in 20, 30, 40 years because they will have a testosterone level to compare things to when you you are older. I think all men should get this done so they have a baseline level.
Even if you have to pay out of pocket for it, its less than you’ll pay in the long run for a testosterone supplement and will give you piece of mind, decades from now.
Joe,
I wish I found your site before I researched the various ingredients in Syntheroid. I found most of my information on Wikipedia but had been distracted by my son so didn’t finish my research re: Forskolin. You mentioned that had some valid tests which appeared to increase Testosterone.
WebMd stated the following;
“However, currently there is no reliable scientific information that shows Coleus forskohlii extracts taken by mouth are effective.”
Do you have additional information on this supplement? I am turning 48 next month and have had a recurrent issue with tennis elbow and still feeling pain from a surgery to repair some torn muscle in my shoulder from 2 years ago. I’m not quite ready to give up rock wall climbing or kayaking and would still like to work out at the gym and build up some muscle again. I’d also like to increase my libido for my wife’s benefit. If you have actually found that the research suggests Forskolin works I’d have my T-levels checked before and after to see if there is a difference. Could recommend a particular manufacturer?
Hi Kevin,
I definitely can empathize with you about tennis elbow! Ive had a bad case of it myself for a couple of months! As for Coleus forskohlii, I’ve only seen one study where it raised Testosterone levels and here it is :
http://www.ncbi.nlm.nih.gov/pubmed?term=Body%20composition%20and%20hormonal%20adaptations%20associated%20with%20forskolin%20consumption%20in%20overweight%20and%20obese%20men.
I referenced this study in my review of Forskolin for weight loss http://supplementclarity.com/coleus-forskohlii-forskolin-weight-loss/ and I pointed out the problems with the study. Its also only one study that’s never been duplicated as far as I know and I think this is why WebMd said there was no good proof that it works. I can’t disagree with them because I also would like to see better research.
If you try Forskolin, get your testosterone levels checked now and then after a month of using Forskolin and see if it changes anything. I wish I could recommend a particular product but its hard to because I dont see any good proof on any of them. I’d say find a product that is made buy a company that you have heard of (they likely have a reputation they want to protect and likely are putting what they say they are in their products). If you do this let me know if your blood tests showed any differences.
are there any test boosters that actually tested that work?
Shaun. I have admittedly not looked at many testosterone boosters but as a rule I am suspicious of any supplement that claims to raise testosterone levels. I think the best thing I can say is test your T levels first and try the product for a month and then have them tested again to see if there is any difference. In the end, I think that will be the best – and cheapest – way to go.
Joe
I am also going to start taking synthroid since i want to jack up in weight. I did find your reviews very helpful and i will take them into consideration. Synthroid has been one of the only testo boosters that i have found online with a decent put out. I will also have my testo check before starting and will update when having results
Rick
Rick, sounds good and I will look forward to learning the results. Much success!