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Updated July 2026. Beverly Hills MD Dermal Repair Complex is an anti-aging supplement promoted for wrinkles, sagging skin, crepey skin, skin elasticity, and stronger-looking hair and nails. The formula contains collagen, hyaluronic acid, MSM, saw palmetto, wild yam, silica, vitamin A, and several B vitamins. Some of those ingredients have human research behind them. However, that does not automatically prove Dermal Repair Complex works. The complete supplement does not appear to have been tested in a published clinical trial, and six of its most important ingredients are hidden inside a 620 mg proprietary blend.

In this Beverly Hills MD Dermal Repair Complex review, I will compare the formula with the amounts used in human studies, examine its claims, discuss possible side effects, and help you decide whether it is worth the money.

Beverly Hills MD Dermal Repair Complex: Key Facts

What Is Beverly Hills MD Dermal Repair Complex?

Beverly Hills MD Dermal Repair Complex is an oral anti-aging supplement marketed to reduce the appearance of wrinkles, crepey skin, sagging skin, and other visible signs of aging. It is also promoted for improving skin hydration and elasticity and supporting healthier-looking hair and nails.

Unlike a cream or serum applied directly to the skin, Dermal Repair Complex is taken by mouth. The formula contains hydrolyzed collagen, MSM, hyaluronic acid, saw palmetto, wild yam, silica, vitamin A, and several B vitamins.

Beverly Hills MD says the supplement works from the inside by supporting collagen, skin moisture, and hormone-related changes associated with aging. However, the complete Dermal Repair Complex formula does not appear to have been tested in a published clinical trial. The evidence comes mainly from studies of individual ingredients, often at doses that may differ from those in this supplement.

Who Makes Beverly Hills MD Dermal Repair Complex?

Dermal Repair Complex is made by Beverly Hills MD, an anti-aging skincare and supplement company founded in 2014 by plastic surgeons Dr. John Layke and Dr. Payman Danielpour.

While their medical backgrounds add credibility to the company, that does not prove Dermal Repair Complex works. The supplement still needs to be judged by the research on its formula, ingredients, and dosages.

Beverly Hills MD Customer Service

• Phone: 877-828-5528
• Email: support@beverlyhillsmd.com

Beverly Hills MD Dermal Repair Complex Ingredients

The current Beverly Hills MD website lists the following Supplement Facts for two capsules:

The 620 mg blend contains:

1. Hydrolyzed collagen
2. Saw palmetto fruit powder
3. MSM
4. Wild yam root extract
5. Hyaluronic acid
6. Silica

The other ingredients are rice bran and hypromellose, which is used to make the capsule

The Biggest Problem With Dermal Repair Complex: Undisclosed Ingredient Doses

The biggest weakness of Beverly Hills MD Dermal Repair Complex is its 620 mg proprietary blend. The label lists six ingredients but does not reveal how much of each one the supplement provides:

• Hydrolyzed collagen
• Saw palmetto
• MSM
• Wild yam
• Hyaluronic acid
• Silica

This makes it difficult to compare Dermal Repair Complex with the doses used in human studies.

For example, the entire blend weighs only 620 mg. Therefore:

• The collagen dose must be less than 620 mg.
• The MSM dose must be less than 620 mg.
• The formula cannot provide the 1,000 to 3,000 mg of MSM tested in a published human skin-aging study
• We cannot tell whether it supplies approximately 120 mg of hyaluronic acid, an amount used in several successful trials.
• We cannot determine whether any ingredient is present at a clinically useful dose.

Ingredients are generally listed from greatest to smallest amount. Since hydrolyzed collagen appears first, it should make up more of the blend than the ingredients listed after it. However, collagen still shares the 620 mg total with five other ingredients.

This does not prove Dermal Repair Complex cannot work. It means the Supplement Facts label does not provide enough information to determine whether its doses match those used in clinical research.

Is Beverly Hills MD Dermal Repair Complex Clinically Proven?

No. I could not locate a published, peer-reviewed clinical trial testing the complete Beverly Hills MD Dermal Repair Complex formula against a placebo.

This does not mean the supplement cannot work. It means the finished product has not been clinically proven to reduce wrinkles, tighten sagging skin, improve crepey skin, or produce the other results described in its advertising.

Some Dermal Repair Complex ingredients have been studied separately. Human trials have reported benefits from oral collagen, hyaluronic acid, and MSM. However, those studies often used specific ingredients and doses that may differ from the amounts in Dermal Repair Complex.

While this is good, Research on individual ingredients does not prove that a finished supplement works.

To clinically prove Dermal Repair Complex works, researchers would need to give the actual supplement to one group of people, give a placebo to another group, and compare changes in wrinkles, hydration, elasticity, skin firmness, or sagging under controlled conditions.

Until that type of study is published, the evidence for Dermal Repair Complex comes mainly from:

• Studies of individual ingredients
• Research using different dosages
• Studies of branded or standardized ingredients not identified on the label
• Customer reviews and before-and-after pictures
• The company’s explanation of how the ingredients may work

Let’s look at the ingredients that matter most.

Hydrolyzed Collagen

Hydrolyzed collagen is collagen that has been broken into smaller peptides to make it easier to digest and absorb. Collagen is an important structural protein in the skin and helps support firmness and elasticity.

Human research suggests oral collagen supplements may modestly improve skin hydration, elasticity, and wrinkles. A 2023 meta-analysis of 26 randomized controlled trials involving 1,721 participants found that hydrolyzed collagen improved skin hydration and elasticity compared with a placebo. However, the researchers also found considerable differences among the studies and noted that study quality and funding may have influenced some results.

In one randomized, placebo-controlled trial, women who took 1,650 mg of collagen peptides daily for 12 weeks showed improvements in skin hydration, elasticity, and wrinkles.

Another randomized, double-blind, placebo-controlled trial involved 64 adults who took 1,000 mg of low-molecular-weight fish collagen peptides or a placebo daily for 12 weeks. The collagen group showed greater improvements in skin hydration, several wrinkle measurements, and some measurements of skin elasticity.

How Does the Dermal Repair Complex Collagen Dose Compare?

Beverly Hills MD does not disclose how much hydrolyzed collagen Dermal Repair Complex contains. We only know that collagen is the first ingredient in a proprietary blend totaling 620 mg.

Because the blend also contains saw palmetto, MSM, wild yam, hyaluronic acid, and silica, the collagen dose must be less than 620 mg per two-capsule serving.

That is lower than the amounts used in the two clinical trials discussed above:

• One study used 1,000 mg of low-molecular-weight fish collagen peptides per day.
• Another study used 1,650 mg of collagen peptides per day.

This does not prove that less than 620 mg of collagen cannot work. Different collagen peptides may produce effects at different doses. However, Beverly Hills MD does not identify the source, molecular weight, peptide composition, or exact amount of collagen in Dermal Repair Complex.

Therefore, there is no way to know whether its collagen matches the ingredients or doses used in successful clinical trials.

Collagen Evidence Verdict

Evidence for collagen supplements: Reasonable
Evidence for the amount in Dermal Repair Complex: Uncertain

Hyaluronic Acid

Hyaluronic acid is a substance naturally found in the skin, joints, and other connective tissues. It attracts and holds water, which helps the skin stay hydrated and may make fine lines appear less noticeable.

Most people associate hyaluronic acid with moisturizers and injectable fillers. However, several randomized, placebo-controlled studies have also tested oral hyaluronic acid supplements.

In a 2015 study, 61 adults with dry skin took either 120 mg of hyaluronic acid or a placebo each day for six weeks. The hyaluronic acid groups experienced greater improvements in skin moisture than the placebo group.

A 2017 study involved 60 adults with crow’s-feet wrinkles. Participants took 120 mg of hyaluronic acid or a placebo daily for 12 weeks. One hyaluronic acid group had significantly reduced wrinkles after eight weeks, and both groups showed improvements in several wrinkle measurements.

In another randomized, placebo-controlled trial published in 2021, 40 adults took 120 mg of hyaluronic acid or a placebo daily for 12 weeks. Compared with placebo, the hyaluronic acid group showed improvements in wrinkles, skin moisture, elasticity, and transepidermal water loss.

These studies suggest that oral hyaluronic acid may modestly improve skin hydration, elasticity, and certain wrinkle measurements. However, the trials were relatively small, and some of the researchers were employed by the company associated with the hyaluronic acid ingredient.

Does Dermal Repair Complex Provide Enough Hyaluronic Acid?

We do not know.

Hyaluronic acid appears near the bottom of the six-ingredient proprietary blend. It is possible for the formula to contain 120 mg, but the label does not prove it does.

Hyaluronic Acid Evidence Verdict

Evidence for oral hyaluronic acid: Promising
Evidence for the Dermal Repair Complex dose: Unknown

MSM

MSM, short for methylsulfonylmethane, is a sulfur-containing compound commonly found in joint, exercise recovery, and beauty supplements. Sulfur is involved in connective-tissue proteins, but that alone does not prove MSM supplements reduce wrinkles or tighten skin.

The most relevant human study I located was titled Beauty from within: Oral administration of a sulfur-containing supplement methylsulfonylmethane improves signs of skin ageing.

The study had two parts. In the first part, 20 women took either 3,000 mg of MSM or a placebo daily for 16 weeks. Compared with placebo, MSM reduced facial wrinkles and skin roughness.

In the second part, 63 women took either 1,000 mg or 3,000 mg of MSM daily for 16 weeks. Both doses improved some measurements of wrinkles, skin firmness, elasticity, and hydration. The researchers concluded that 1,000 mg per day appeared sufficient to reduce certain signs of facial aging.

How Does the Dermal Repair Complex MSM Dose Compare?

Beverly Hills MD does not disclose how much MSM Dermal Repair Complex contains.

This does not prove that a lower MSM dose cannot work. But the results of the published study cannot be directly applied to Dermal Repair Complex.

MSM Evidence Verdict

Evidence that MSM may improve certain signs of skin aging: Limited but promising

Evidence that Dermal Repair Complex provides a clinically tested MSM dose: Weak

Saw Palmetto

Saw palmetto is best known as an ingredient in prostate and hair-loss supplements. It contains fatty acids and plant sterols that may affect 5-alpha-reductase, an enzyme involved in converting testosterone into dihydrotestosterone, better known as DHT.

DHT plays an established role in androgenetic alopecia, also called male or female pattern hair loss. This gives saw palmetto a plausible reason for appearing in supplements marketed for thinning hair.

In one 16-week randomized, placebo-controlled study, 80 men and women with mild-to-moderate androgenetic alopecia received either 400 mg of a standardized saw palmetto oil, a topical saw palmetto treatment, or the corresponding placebo. The oral supplement reduced hair fall, modestly increased hair density, and lowered blood DHT levels compared with placebo. However, the study tested a standardized saw palmetto oil containing 2% to 3% beta-sitosterol, not ordinary saw palmetto fruit powder.

Does Saw Palmetto Improve Wrinkles or Sagging Skin?

Beverly Hills MD says saw palmetto helps reduce the visible effects of “skin-destroying DHT” and supports youthful skin elasticity.

I could not locate a published human clinical trial showing that oral saw palmetto reduces wrinkles, improves skin firmness, increases elasticity, or tightens sagging skin.

Although androgens affect the skin, that does not prove that lowering DHT will reverse visible skin aging. In fact, age-related changes in skin hormones are complicated, and lower androgen activity is not automatically beneficial for aging skin.

Therefore, the evidence for saw palmetto in Dermal Repair Complex relates mainly to possible hair benefits, not proven anti-wrinkle or skin-tightening effects.

How Does the Dermal Repair Complex Saw Palmetto Dose Compare?

Beverly Hills MD lists saw palmetto fruit powder as the second ingredient in its 620 mg proprietary blend but does not disclose the amount.

The company also does not state that the saw palmetto is standardized for fatty acids, beta-sitosterol, or any other active compound.

Saw Palmetto Evidence Verdict

Evidence that standardized saw palmetto may help androgen-related hair loss: Limited but promising

Evidence that saw palmetto reduces wrinkles or sagging skin: Insufficient

Evidence that Dermal Repair Complex provides a clinically tested saw palmetto dose: Unknown

Wild Yam Root Extract

Wild yam contains diosgenin, a plant compound that can be used in a laboratory to manufacture steroid hormones.

That does not mean the human body converts wild yam into DHEA, estrogen, or progesterone when its taken as a supplement. Claims that wild yam naturally “balances” female hormones should be treated cautiously.

The label also does not identify:

• The amount of wild yam
• The concentration of the extract
• The amount of diosgenin
• The specific skin benefit expected from the dose

Wild yam may sound appropriate in a formula marketed toward age-related hormonal changes, but direct proof that oral wild yam improves wrinkles, skin firmness, or sagging is appears to be lacking.

Wild Yam Evidence Verdict

Evidence for skin aging: Insufficient

Silica

Silica provides silicon, a trace element present in connective tissues, hair, skin, and nails.

Some small studies have investigated specific forms of silicon for hair, nail, and skin properties. However, the Dermal Repair Complex label does not identify the form or amount of silica, making a meaningful research comparison difficult.

Silica Evidence Verdict

Evidence for skin, hair, and nails: Preliminary
Evidence for this formula: Unknown

What About the Vitamins?

Dermal Repair Complex contains vitamin A and a large assortment of B vitamins. Most provide several times the Daily Value.

Unless someone has a deficiency or an really poor diet, large amounts of B vitamins do not automatically produce younger-looking skin.

Biotin

Biotin is widely promoted for hair and nails, but biotin deficiency is uncommon.

The supplement provides 2,500 mcg, which is 8,333% of the Daily Value. Some older research reported improvements in brittle nails with 2.5 mg, the same as 2,500 mcg, but the evidence was limited and did not establish that biotin improves normal nails or reverses skin aging in people who are not deficient.

High-dose biotin can also interfere with certain medical tests, including some tests for thyroid hormones, vitamin D, and troponin. Incorrect troponin results are especially important because troponin testing may be used when a heart attack is suspected.

Tell your doctor and laboratory personnel that you take biotin before undergoing bloodwork.

Niacinamide

The Dermal Repair Complex provides 50 mg of niacin as niacinamide, also called nicotinamide. Niacinamide is a form of vitamin B3 and is different from nicotinic acid, the form of niacin best known for causing skin flushing.

Nicotinic acid can cause warmth, redness, itching, and tingling at supplemental doses of about 30 to 50 mg or more. Niacinamide does not usually cause this flushing reaction because it has a different chemical structure.

Does Niacinamide Help Aging Skin?

Topical niacinamide has good evidence for improving certain signs of aging skin.

In one randomized, double-blind study, 50 women applied a moisturizer containing 5% niacinamide to one side of the face and a control moisturizer to the other side for 12 weeks. The niacinamide treatment improved fine lines and wrinkles, hyperpigmented spots, skin texture, red blotchiness, yellowing, and elasticity compared with the control.

Another randomized study involved 30 women who applied a cosmetic containing 4% niacinamide around one eye and a control product around the other eye for eight weeks. The niacinamide product produced greater improvements in wrinkle grades and skin-surface roughness.

However, these studies tested niacinamide applied directly to the skin. They do not prove that taking 50 mg of oral niacinamide reduces wrinkles, improves elasticity, or tightens sagging skin.

Oral niacinamide has been studied for other skin-related purposes. For example, 500 mg twice daily reduced new nonmelanoma skin cancers in high-risk adults during a 12-month clinical trial. That is a different use and a much larger dose than the 50 mg in Dermal Repair Complex. It did not establish an anti-wrinkle benefit.

How Does the Dermal Repair Complex Niacinamide Dose Compare?

Dermal Repair Complex provides 50 mg of niacinamide daily.

However, I could not locate a published clinical trial showing that 50 mg of oral niacinamide improves wrinkles, sagging skin, crepey skin, hydration, or skin elasticity.

Niacinamide Evidence Verdict

Evidence that topical niacinamide improves certain signs of aging skin: Good

Evidence that 50 mg of oral niacinamide reduces wrinkles or sagging skin: Insufficient

Likelihood of causing a niacin flush: Low

Vitamin B6

Dermal Repair Complex provides 10 mg of vitamin B6.

This is below the current U.S. adult upper limit of 100 mg per day. However, the European Food Safety Authority established a lower adult upper limit of 12 mg per day in 2023 because long-term excessive vitamin B6 can damage nerves. Someone taking this supplement plus a multivitamin, B-complex, energy product, or fortified drink could easily consume more.

Folate

The formula supplies 1,333 mcg DFE, including 800 mcg of folic acid.

The adult upper limit for folic acid from supplements and fortified foods is 1,000 mcg per day. Therefore, Dermal Repair Complex alone provides 80% of that limit before counting a multivitamin or fortified foods.

This is another reason to check your other supplements rather than stacking several products containing high-dose B vitamins.

Does Dermal Repair Complex Help Wrinkles?

It might help some people with fine wrinkles, particularly if it supplies a useful amount of hyaluronic acid or collagen.

However, the evidence does not show that Dermal Repair Complex:

• Erases deep wrinkles
• Produces a facelift-like effect
• Significantly lifts jowls
• Tightens loose skin throughout the body
• Reverses severe crepey skin
• Replaces sunscreen, retinoids, moisturizers, or medical treatments

Most oral collagen and hyaluronic acid studies report modest changes measured with specialized instruments. That is not the same as dramatic before-and-after photographs.

People with fine lines, dryness, or mild changes in elasticity would be more likely to notice a difference than people with deep wrinkles or considerable skin sagging.

Does It Help Crepey or Sagging Skin?

The company specifically markets the supplement for thin, crepey, and sag-prone skin.

Some collagen, hyaluronic acid, and MSM studies suggest possible benefits for hydration and elasticity. However, I could not locate a clinical trial showing that the complete Dermal Repair Complex formula visibly lifts sagging neck skin, jowls, arms, legs, or the abdomen.

Hydration can temporarily make dry, crepey skin look smoother. That is different from rebuilding enough connective tissue to tighten substantially loose skin.

Does Dermal Repair Complex Help Hair and Nails?

Biotin, collagen, saw palmetto, and silica are all found in hair or nail supplements.

Dermal Repair Complex might help someone whose brittle nails or hair problems are related to poor nutrition or a deficiency. However:

• Biotin deficiency is rare.
• Saw palmetto hair research is limited.
• The collagen and silica amounts are not disclosed.
• Hair shedding can have many causes, including thyroid problems, iron deficiency, medication, illness, weight loss, stress, and hormonal changes.

Persistent hair loss should be evaluated rather than automatically treated with a beauty supplement.

How Long Does Dermal Repair Complex Take to Work?

The company says many customers notice a visible difference within approximately one month but also states that consistent use produces the best results.

Based on studies of collagen, hyaluronic acid, and MSM, a more reasonable evaluation period would be eight to 12 weeks.

Take clear photographs before starting:

• Use the same room and lighting.
• Stand in the same position.
• Use the same camera.
• Do not change filters or beauty settings.
• Photograph the areas that concern you.
• Avoid introducing several new skin products at the same time.

Otherwise, it becomes difficult to know whether any apparent change is real or what caused it.

Dermal Repair Complex Before-and-After Pictures

Before-and-after photographs can be useful, but they are also easy to influence.

Differences in lighting, makeup, facial expression, camera distance, hydration, posture, and image processing can make wrinkles and sagging look better or worse.

Pay closest attention to pictures that:

• Show an older adult with visible wrinkles before treatment
• Use identical lighting and camera angles
• Include a specific treatment period
• Disclose other skincare treatments
• Do not come from a seller or affiliate
• Show unedited, high-resolution images

Testimonials from younger people with few visible wrinkles tell us little about whether the supplement helps advanced skin aging.

Beverly Hills MD Dermal Repair Complex Side Effects

Dermal Repair Complex may be tolerated by many healthy adults, but “natural” does not mean side-effect-free.

Possible issues include:

• Upset stomach
• Nausea
• Bloating
• Headache
• Skin rash or allergic reaction
• Bright-yellow urine from riboflavin
• Laboratory-test interference from biotin
• Unnecessary duplication of B vitamins from other supplements

The current formula uses niacinamide, so a strong niacin flush is less likely than it would be with nicotinic acid.

Who Should Speak to a Doctor First?

Check with your physician or pharmacist before taking Dermal Repair Complex if you:

• Are pregnant or breastfeeding
• Have a hormone-sensitive medical condition
• Take hormone replacement therapy
• Take blood-thinning or antiplatelet medication
• Have liver or kidney disease
• Have an upcoming operation
• Take several other vitamin supplements
• Are being evaluated for thyroid, heart, or hormone problems
• Have a history of prostate or hormone-sensitive cancer

The product itself has not been shown to cause these conditions. The caution is based on its ingredients, possible drug interactions, and the lack of a clinical safety trial on the complete formula.

Can Men Take Dermal Repair Complex?

The company markets the product primarily to women, but most of its nutritional ingredients would not be expected to work only in women.

Men should still review the saw palmetto, folic acid, biotin, and vitamin B6 content with their doctors when appropriate, especially if they have prostate disease, take medications, or regularly undergo laboratory testing.

It should not be assumed that saw palmetto in this proprietary blend will treat an enlarged prostate or hair loss. Its amount is not disclosed, and the product is not intended to treat either condition.

Is Dermal Repair Complex Vegan?

No. Hydrolyzed collagen is animal-derived unless a product specifically states otherwise.

The official page does not clearly identify the collagen source. People with fish, shellfish, beef, pork, or other animal allergies should ask Beverly Hills MD to identify the source before ordering.

How Do You Take It?

The suggested dosage is two capsules with eight ounces of water once daily with a meal.

Taking it with food may reduce digestive discomfort. Do not assume taking more will work faster.

How Much Does Dermal Repair Complex Cost?

Prices change with promotions, bundles, subscriptions, and account status. The official site has recently shown one-time pricing beginning around $39.95 per bottle, with lower per-bottle prices for larger orders.

Each bottle contains 60 capsules and lasts 30 days when used as directed.

Check the final checkout page carefully. A discounted subscription is not the same as a one-time purchase.

Important Subscription Details

Beverly Hills MD offers automatic deliveries. Under the current Dermal Repair Complex subscription terms, customers may be billed and sent another order approximately every 30 days until they cancel.

The listed monthly subscription prices are:

• One jar: $35.95
• Two jars: $68.40
• Three jars: $91.80

The company says subscriptions can be canceled without an early cancellation fee by contacting customer service.

Do not choose the subscription merely because the initial price looks lower. Choose it only if you knowingly want recurring charges and shipments.

Dermal Repair Complex Money-Back Guarantee

Supplements purchased from the Beverly Hills MD website have a 90-day return period beginning on the date the order ships, not the date it arrives.

You must:

1. Contact the company or submit its return form.
2. Obtain return authorization and instructions.
3. Return the bottles, including empty bottles.
4. Pay the return-shipping cost.

The refund does not include shipping charges. Products bought from third-party sellers are subject to the seller’s return policy rather than Beverly Hills MD’s guarantee.

Keep every bottle until you decide whether you are satisfied.

Dermal Repair Complex Pros and Cons

Pros

• Contains several ingredients with some human skin research
• Hyaluronic acid may improve skin hydration and fine wrinkles
• Collagen research is generally promising
• MSM has limited human evidence for wrinkles and skin texture
• Provides a simple two-capsule daily dosage
• Comes with a 90-day return period when bought from the company
• The inactive ingredient list is short

Cons

• No published clinical trial on the complete formula was located
• Six main ingredients are hidden in a 620 mg proprietary blend
• The collagen dose appears low compared with many successful studies
• The MSM dose must be below amounts used in successful trials
• The hyaluronic acid amount is not disclosed
• Claims involving DHT and significant skin tightening are not well proven
• Contains very high percentages of several B vitamins
• Biotin may interfere with medical tests
• The subscription renews automatically unless canceled
• The guarantee starts on the shipping date and requires bottles to be returned

Is Dermal Repair Complex a Scam?

I would not call it a scam.

The company discloses the ingredients, dosage, subscription terms, and return policy. Several ingredients have legitimate scientific interest.

However, legitimate ingredients do not prove that every marketing claim is accurate. The lack of disclosed doses and absence of a clinical trial on the complete formula make it impossible to confirm that Dermal Repair Complex produces the lifting, firming, and wrinkle-reducing results suggested by its advertising.

A more accurate description would be an unproven formula containing some researched ingredients.

Is Dermal Repair Complex Worth It?

Dermal Repair Complex may be worth considering if:

• You prefer capsules over collagen powder.
• You understand that results may be modest.
• You want to try it for eight to 12 weeks.
• You are comfortable with the undisclosed blend.
• You will use the return policy if it does not help.
• Your doctor has no concerns about the ingredients.

It may not be worth it if:

• You expect dramatic lifting or wrinkle removal.
• You already take a high-dose B-complex supplement.
• You frequently undergo biotin-sensitive blood tests.
• You dislike automatic subscriptions.
• You want a product whose complete formula has been clinically tested.

What Would Make the Formula Better?

Beverly Hills MD could make Dermal Repair Complex easier to evaluate by:

1. Disclosing the amount of every ingredient.
2. Conducting a randomized, double-blind, placebo-controlled trial on the finished product.

The company’s founders are plastic surgeons and should have access to the expertise needed to conduct a meaningful clinical trial.

Does Beverly Hills MD Dermal Repair Complex Really Work?

Dermal Repair Complex contains several ingredients that could plausibly support skin hydration, fine wrinkles, hair, or nails. Hyaluronic acid has the most convincing possibility of working at a dose that could fit inside the formula. Collagen and MSM also have human research, but the amounts in this supplement appear lower than many clinically tested doses.

I would expect any benefits to be subtle and more likely to involve hydration, skin texture, or fine lines than dramatic lifting of jowls, loose skin, or deep wrinkles.

Frequently Asked Questions

Does Dermal Repair Complex remove wrinkles?

There is no published clinical trial proving the complete supplement removes wrinkles. Some of its ingredients may modestly improve fine wrinkles or hydration, but deep wrinkles are unlikely to disappear.

Does Dermal Repair Complex tighten loose skin?

The company promotes firmer and lifted-looking skin, but no clinical trial on the complete formula proves that it tightens substantially loose skin or jowls.

Can Dermal Repair Complex help crepey skin?

Improved hydration may make dry, crepey skin appear smoother. Evidence that the supplement rebuilds enough skin structure to reverse significant crepey skin is lacking.

How soon will I see Dermal Repair Complex results?

Allow approximately eight to 12 weeks before judging the product. Compare standardized photographs rather than relying on memory.

Does Dermal Repair Complex contain hormones?

The label does not list estrogen, progesterone, DHEA, or other hormones. Wild yam does not automatically become human hormones after it is swallowed.

Can Dermal Repair Complex cause weight gain?

None of the disclosed ingredients has been proven to cause meaningful weight gain when taken at the label dosage. Sudden weight changes should be investigated rather than automatically blamed on the supplement.

Does it contain fish or shellfish?

The current official product page does not clearly identify the animal source of its hydrolyzed collagen. People with serious allergies should obtain written confirmation from Beverly Hills MD before using it.

Is Dermal Repair Complex FDA approved?

No dietary supplement of this type is FDA approved for effectiveness before it is sold. That does not by itself mean the product is unsafe or fraudulent. It means the manufacturer, rather than the FDA, is responsible for ensuring that the supplement is properly labeled and legally marketed.

Can I buy Dermal Repair Complex on Amazon?

It may be available from third-party marketplaces. However, Beverly Hills MD’s 90-day guarantee applies to purchases made through its own website. Check the seller, expiration information, seal, storage conditions, and return policy before purchasing elsewhere.

My Final Verdict

Dermal Repair Complex is based on an interesting idea, and I would not dismiss every ingredient in it. Oral collagen, MSM, and hyaluronic acid deserve more attention. Beverly Hills MD Dermal Repair Complex contains several ingredients that may help the skin. Human studies suggest that collagen, hyaluronic acid, and MSM can improve skin hydration, fine wrinkles, or elasticity in some people.

The problem is that Beverly Hills MD does not reveal how much of each ingredient the supplement contains. Collagen, saw palmetto, MSM, wild yam, hyaluronic acid, and silica are all combined in a proprietary blend totaling only 620 mg.

That makes the formula difficult to judge.

Dermal Repair Complex may provide modest benefits for skin moisture, texture, or fine lines, but there is no good evidence that it will dramatically tighten loose skin, lift jowls, or erase deep wrinkles.

My opinion is that the supplement is possible but unproven. I would prefer a product that clearly lists the amount of collagen, MSM, and hyaluronic acid it provides.

Have you tried Beverly Hills MD Dermal Repair Complex? How long did you take it, and what did you notice?

Updated November 7 2024. Aquamin is a broad-spectrum, multi-mineral plant-sourced dietary supplement. The minerals are derived from red seaweed (Lithothamnion calcareum). The supplement provides a good source of calcium, magnesium, and 72 other trace minerals and is touted to help build bone and reduce arthritis pain. So does Aqumin work? Does it build bone or reduce arthritis pain? What about side effects? This review will focus on the research. If you know the clinical research, you'll have a better idea if this plant-sourced, red mineral algae supplement is right for you.

What Is Aquamin?

Aquamin -not to be confused with AquaMan – is an aquatic multi-mineral supplement. The name literally means aquatic minerals. It's a calcium/magnesium supplement derived from red seaweed (algae) that are harvested a few times a year from Iceland. Magnesium hydroxide is the form of magnesium used in the supplement.

Aquamin calcium is made up of calcium carbonate.  Both calcium and magnesium make up most of the aquatic minerals. While not stated on Nutrition Facts labels, Aquamin is also a source of 72 trace minerals such as but not limited to:

Aluminum,  Arsenic,  Barium,  Boron

Calcium, Cadmium, Cesium,  Chloride,

Chromium,  Cobalt,  Copper,  Floride,

Germanium,  Gol,d  Iodine,  Iridium,

Lead,  Lithium,  Lutetium,  Magnesium

Don't be alarmed by the presence of minerals like arsenic and lead, as these naturally occur in red algae. Their levels are very low and are measured in parts per million (ppm). The amounts of trace minerals may fluctuate according to the season of harvest and the mineral content of the water the algae live in.

Who Makes Aquamin

The company is Margot Ltd. The Margot company is located in Cork, Ireland, and has been in business since 1993. The red algae are harvested from Bildudalur, Iceland.  While the supplement is not patented, Margot is the ONLY company permitted to harvest red algae from Iceland. This means all supplements containing Aquamin are obtained from Margot.

Check out this video for more insights.

In the US, Margot partners with another company called Stauber Performance Nutrition (StauberUsa.com), located in California. Stauber is a US-based dietary supplement ingredients company that's been in business since 1969. Stauber provides ingredients to many dietary supplement companies. Aquamin is one of the ingredients they offer.

Where Does Aquamin Come From

Lithothamnion calcareum is the red algae the supplement is derived from. Seaweed is a type of algae. This is why these words are used interchangeably when describing the supplement.  The algae are harvested from the Icelandic coast in the village of Bildudalur. The calcium in Aquamin is said to be 3 to 4 times more bioavailable than other forms of calcium.

Where Can You Buy Aquamin?

Many supplements contain the red seaweed multi mineral compounds such as these:

• Natures Answer Marine Based Calcium Magnesium
• NOW Red Algae Calcium capsules
• NATURELO Bone Strength – Plant-Based Calcium
• PlantFusion Calcium Vegan Vitamin

Some of these supplements may be available at local stores like CVS, Vitamin Shoppe, GNC, Walgreens, Walmart, Krogers, and Costco to name a few. To know for sure, check the Supplement Facts label to see if “Aquamin” is mentioned.

Is it Bio-Available?

Can we absorb marine-sourced multi-mineral? In one study, researchers noted that magnesium in red algae (magnesium chloride) was better absorbed than magnesium oxide.

In another investigation, researchers observed that the calcium carbonate in Aquamin was better absorbed than calcium carbonate alone when given to premenopausal.  This same study also noted parathyroid hormone levels (PTH) were lower up to 4 hours after the supplement was taken. This was more than when a calcium carbonate supplement was taken. Parathyroid hormone is a necessary hormone, but too much can weaken bones and contribute to osteoporosis.

Aquamin Research

So what are the benefits of red mineral algae calcium?  To date, there are about 30 studies on Aquamin. Most of the research, though is on mice and isolated cells. To make this review easier, let's divide the research into different parts. Let's also focus mostly on human research.

Osteoporosis/ Bone Research

Study 1

In rats, the supplement has been shown to maintain bone strength. In isolated cells, Aquamin improved bone mineralization in bone cells called osteoblasts. Isolated cell studies have also shown the supplement improves bone formation.

All very good. But what about people?

Study 2

Parathyroid hormone (PTH) helps us absorb calcium from food, and when needed, it also pulls calcium from our bones. In theory, lowering PTH levels that are too high may help preserve bone density. In one small study (12 premenopausal women) Aquamin was shown to be superior at suppressing PTH levels than calcium carbonate. This study also noted the calcium in Aquamin was absorbed better than calcium carbonate alone.

In theory, better absorption and lower PTH levels might mean Aquamin helps osteoporosis. But it will take better research to know for sure.

Study 3

In one 2 year-long study, 300 postmenopausal women were randomly given:

• Aquamin (800 mg)
• Aquamin + a probiotic fiber called NutraFlora
• Placebo (sugar)

While overall bone density did not change, the combination of Aquamin plus the NutraFlora fiber appeared to slow bone loss more than the placebo or the Aquamin supplement alone.

Study 4

Vigorous exercise can raise parathyroid hormone (PTH) levels in young men. Calcium reduces PTH during exercise. But what about older women? In one investigation researchers recruited 33 older women and had them walk for 1 hour quickly. The women were given 4-6 oz of Aquamin calcium or a placebo.

Which lowered PTH levels the most?

The Aquamin supplement seemed to slow the rise in parathyroid hormone compared to the placebo (that's good). But, in my opinion, this study is unrealistic because the women consumed the calcium beverage every 15 minutes during exercise. That's not what people will be doing in the real world. Also, two different amounts of calcium were used. This could have altered the results.

Aquamin Arthritis Research

Study 1

To see if the supplement helps osteoarthritis symptoms, researchers gave 29 people either 2400 mg of Aquamin or a placebo for 12 weeks. Results showed improvements in joint range of motion and walking distance. They also appeared to need fewer pain medications like aspirin and ibuprofen. While encouraging, the study has some issues:

1. Several people dropped out. The study started with 29 people but only 14 completed it.
2. People were asked to cut back on pain drugs (NSAIDs) like ibuprofen, but they were still permitted to use Tylenol (acetaminophen) for pain if needed. Could Tylenol use have impacted the results?

Study 2

Researchers gave either Aquamin or a supplement (called AquaPT) to 24 women with osteoarthritis for 6 weeks each. The AquaPT supplement contained Aquamin plus pine bark, and green tea. Both supplements reduced inflammation although the AquaPT showed more of an effect. Most people taking either supplement reported less pain and stiffness too.

Study 3

What about Aquamin plus glucosamine sulfate? Do they work better together? In this investigation, researchers took 50 people with osteoarthritis and split them  into the following 3 groups

1. Placebo
2. Aquamin alone ( 2400 mg/day)
3. Glucosamine sulfate alone (1500 mg)
4. Aquamin (2400 mg/day) plus glucosamine sulfate (1500 mg/day)

While pain, stiffness and walking distance was improved in both the Aquamin and glucosamine groups, those taking the combination of both did not improve. The reasons for this finding are not known.

Aquamin Cancer Research

Can the supplement help cancer? One study in mice appeared to show Aquamin inhibited liver tumor formation. Another mouse study noted the seaweed calcium supplement inhibited colon polyp formation in mice fed a high-fat diet.  Preliminary research also suggests the supplement may reduce the spread of colon cancer.

These findings are very preliminary.  I'm not known is if Aquamin improves colon cancer in humans or prolonged the lives of those with cancer.

Research Summary

Based on human research that could be located it appears Aquamin might:

• slow bone loss
• reduce parathyroid hormone levels
• reduce arthritis pain and stiffness

More research is needed to determine if it reduces osteoporosis.

Any Antioxidant Effects?

Some of the aquatic trace minerals in red seaweed may have antioxidant properties. This might explain some of its benefits although more research is needed. At least one cell study has noted the seaweed calcium supplement does not interfere with the antioxidant effects of Enzogenol (a pine bark extract) and Sunphenon (a green tea extract). That means it seems to play nice with other antioxidants. That's good.

Aquamin vs. Algae Cal

Algae Cal is a popular bone-building supplement that is also derived from red algae. AlgaeCal is derived from Lithothamnion superpositum. Aquamin comes from a similar species of red algae called Lithothamnion calcareum. 

Both Algae Cal and Aquamin have their share of clinical studies.

So which is better? It would take human clinical studies to know for sure. Unfortunately, that research has not yet been conducted.

See the AlgaeCal Review.

Aquamin vs. Glucosamine Sulfate

Glucosamine sulfate a popular arthritis supplement. It may also be used to help sagging skin as well. Glucosamine sulfate has the lion share of arthritis research. Over the years, several studies have found glucosamine sulfate seems to help osteoarthritis pain. There is no glucosamine in Aquamin.

So, do they work better together?

In one study, researchers tried to see if the combination worked better together. Unfortunately, this study failed to show the benefit of adding glucosamine sulfate (1500 mg/ day) to Aquamin. The reason why the combination did not work better is not known.

Some supplements may contain glucosamine HCL, a form that I feel is less effective.  Arthritis supplements may also contain chondroitin sulfate, which this reporter feels should not be used by men until it's proven safe.

How Does It Compare To Calcium Citrate?

Calcium citrate is about 21% elemental calcium. Calcium carbonate is about 40% elemental calcium.  It's the elemental calcium that helps build bones. This means you'd have to take more calcium citrate to get the same amount of elemental calcium found in calcium carbonate. The calcium in Aquamin is calcium carbonate.  No studies comparing aquatic mineral supplements to calcium citrate could be located. On the plus side, calcium citrate can be taken on an empty stomach. It's best to take calcium carbonate supplements with food.

Aquamin vs. Omega XL

Omega XL is a widely popular omega-3 supplement. Omega XL comes from the green-lipped mussel that's harvested from New Zealand. Both supplements have been studied to see if they help arthritis. Both have some positive research too. But it's not known which is best. No studies have compared Omega XL vs Aquamin.

See the Omega XL Review

Aquamin Side Effects

Most studies show Aquamin safety is nothing people need to worry about. Most studies show no significant side effects from this botanically derived mineral supplement. Here are some things to consider. This list is not complete:

• start with less than recommended for the first week
• ask your doctor if you are allergic to seaweed
• if you take medications like blood thinners, ask your doctor
• ask your doctor if you take any medications. Calcium can interact with medications like blood pressure meds and heart drugs.
• stop taking at least 2 weeks before surgery
• if pregnant/breastfeeding, ask your doctor first
• constipation is sometimes reported with calcium supplements
• if you have hypoparathyroidism (low PTH levels), ask your doctor before using
• consider the calcium you already get from foods. This may tell you if you need a calcium supplement

In one study, of older people with arthritis, side effects reported included:

• upper respiratory infections
• gastrointestinal events
• musculoskeletal issues
• increased osteoarthritis pain

But, there were more side effects in those taking a placebo. The placebo group also reported more arthritis pain. As such, the intensity of side effects in those taking the supplement might be minimal.

Aquamin FAQ

1 Does it come from algae or seaweed?

Technically, algae is a type of seaweed. Supplements containing Aquamin may be labeled as red algae. You may have heard the supplement referred to as seaweed calcium. While confusing, both terms pretty much mean the same thing.

2 What is Aquamin TG?

This is one of the forms used in dietary supplements. Aquamin TG has at least 30% calcium.

3 What is Aquamin MG?

The MG in the name refers to magnesium. This form of red algae supplement has more magnesium than Aquamin TG.

4 Do you have to take it with food?

The company says the supplement can be taken on an empty stomach if you prefer.

5 Is it a capsule or powder?

Both. The supplement is available as a powder that you mix in water/juice or gel caps if you prefer.

6 Is it safe?

In the US, Aquamin is generally recognized as safe (GRAS). This is an FDA term. Foods, food additives, and supplements that are GRAS are those which have been consumed by many people for a long time and /or have been reviewed by qualified experts as being safe to consume.

7 Is it vegan?

The supplement comes from red algae seaweed, so yes, it's vegan. All the minerals in the supplement come from seaweed.

8 Is it Kosher?

The supplement is both kosher and halal certified.  Aquamin is also Generally Recognized As Safe (GRAS).

9 Does it have iodine?

Yes. It has been reported that it has about 1.81 micrograms of iodine per gram. That's not much. Whether Aquamin helps the thyroid function better or helps those with hypothyroidism needs more study.

10 How long do supplements last?

Supplements have a shelf life of 3 years from the date of manufacture.

11 Is it organic?

Yes.  It's both organic and non-GMO.

12 Is it environmentally friendly and sustainable?

Yes. The Margot company goes to great lengths to ensure harvesting does not deplete the environment.

13 Does it work better with vitamin D?

Vitamin D improves the absorption of calcium so it makes sense both would work better together. At least one study has demonstrated vitamin D enhances Aquamin calcium uptake by cells.

14 Is it the same as carrageenan?

Carrageenan is a food-thickening agent derived from red algae. It is derived from Chondrus crispus (Irish Moss), while Aquamin comes from another type of red algae seaweed called Lithothamnion calcareum. There is no carrageenan in Aquamin.

15. Can you give it to dogs?

Some dog supplements may contain Aquamin. Does it work? It's possible, but research is lacking. I suggest talking to your veterinarian.

16. What's the active ingredient?

It's important to remember Aquamin has over 72 trace minerals. Calcium and magnesium make up most of those and get a lot of attention.  However, the contribution of other minerals cannot be overlooked. Some of those trace minerals may have antioxidant and anti-inflammatory effects. If Aquamin really works, I don't think you can boil it down to just one mineral.

Is Aquamin Best For Bones?

Aquamin, derived from red algae, will appeal to many who are looking for a plant-based natural multi-mineral supplement.  While the supplement has clinical research, I wish there were a few more human studies. The studies showing less arthritis pain and stiffness are interesting. How well it works may depend on how bad your arthritis is. If you're taking it for osteoporosis, remember it may take at least a year before improvements in bone density are observed.

Heres Aquamin on Amazon

Any Questions or Comments?

Can cinnamon help or prevent prediabetes? Given that almost 40% of Americans have prediabetes (metabolic syndrome) this is a question people are starting to wonder about as they deal with their elevated blood sugar levels. Prediabetes is the forerunner of type II diabetes. So, it's serious. In this review, the research on this simple spice and prediabetics (metabolic syndrome) will be discussed. You'll discover how much works, the brands that have been shown to help, and the side effects you should be aware of.

There Are Different Types of Cinnamon

There are over 250 species of cinnamon. Just a few include:

1. Cassia cinnamon (Cinnamomum cassia)
2. Ceylon cinnamon (Cinnamomum verum)
3. Saigon cinnamon (Cinnamomum loureirii)

While all types are from the same family of trees, there may be differences in how effective they are at lowering blood sugar and A1C levels. Is it possible this is why some studies show the spice works while others show it doesn't?

For example, while Ceylon remains popular among lovers of this spice, studies tend to show it is not effective for type II diabetes. As such, avoid Ceylon cinnamon if you have diabetes.

Most of the blood sugar-lowering proof involves Cassia cinnamon.

Can Cinnamon Help Type II Diabetes

Most studies have used Cassia cinnamon so that's probably what you will see in supplements.  There have been several clinical investigations on this spice and diabetes. Some studies say it helps while others find it doesn't. Here are a couple of those investigations.

Study

In one of the better reports, researchers looked at 10 previous studies which, involved 543 diabetics. The results noted Cassia cinnamon was effective at lowering:

• Blood sugar
• Triglycerides
• Total cholesterol
• LDL cholesterol (bad cholesterol)

These researchers did not see any benefit to A1C levels.

Study

In another study, 109 people with type 2 diabetes were given 1000 mg of cinnamon for 3 months. Those taking the spice showed a slight reduction in A1C levels (about 1%). One downside was there was no placebo group. This study used the Puritans Pride brand of cinnamon.

Summary Of Diabetes Research

• While some of the reports are encouraging, a problem is researchers often use different dosages. In some reports researchers used about 100 mg a day while in others more than 5000 mg a day was used.  If we look at just the successful studies, the sweet spot may be between  500mg -1500mg.
• Not all studies show cinnamon can lower hemoglobin A1C (HBA1c). This measures long-term blood sugar levels and is an important marker for how bad your diabetes is.
• Remember most studies looked at type II diabetes (the most common type)
• Studies tend to show cinnamon does not help type I diabetes

What Does All This Mean?

1. If you have type I diabetes, cinnamon might not help you.
2. If you have type II diabetes (the most common form), it's possible cinnamon may help lower your blood sugar levels, although not all the evidence shows this happens. If you take medications, like metformin or insulin, cinnamon might cause your blood sugar to go to low. So, it's best to speak to your doctor.
3. Ideally, the best thing would be to prevent diabetes from happening in the first place.

What Is Prediabetes?

Prediabetes (metabolic syndrome) is a term used by doctors for those who have several of the following:

1. Having a large waistline (35 to 40 inches for women and men respectively)
2. Higher than normal fasting blood sugar levels (100-125 mg/dl)
3. Elevated blood pressure
4. High triglyceride levels
5. Low HDL levels (good cholesterol)

Prediabetes raises the risk of type II diabetes. So, it's serious.

Almost 40% of US adults have prediabetes. Many aren't aware they have it. If you have some or most of these symptoms, it's best to deal with them now so they don't get out of control and progress to type II diabetes.

So, can cinnamon help prediabetes?

Let's look at the proof.

Cinnamon And Prediabetes

So how much does cinnamon help prediabetes? The good news is there is some research. The bad news is there isnt much of it. Here is a rundown on what we know.

Study

Researchers in both South Korea and the US conducted a 3-month study that involved 54 men and women with prediabetes.  The people ranged in age from 20-70. They were split into the following groups:

• Cinnamon group
• placebo group

The dosage of cinnamon was 1500 mg cinnamon a day (500 mg taken 3 times a day).

Results

Those taking 1500 mg of cinnamon (Solgar brand) which contains Cinnamomum burmannii or Indonesian cinnamon:

• had lower blood sugar levels
• reduced levels of HBA1C

These effects were not seen in those taking the placebo. There were no side effects either (that's good).

HBA1c is a measure of long term blood sugar.  The normal A1C level is less than 6. In this study, the A1C levels of some people were reduced so much they would no longer be classified as prediabetic.

Study

In a smaller investigation, researchers looked at the effects of 12 g  of cinnamon a day for 12 weeks. Despite the higher dosage, these researchers saw no change in insulin sensitivity, blood sugar or A1C levels. Oddly, it was the placebo group which showed a reduction in insulin levels. On the plus side, there were no liver problems reported despite the high dosage used.

What Does This Mean?

1. Few studies have looked at cinnamon helping prediabetes
2. No study has yet shown the spice can prevent you from getting type II diabetes

Any Cinnamon Side Effects?

• Start with less than recommended for the first week
• Pregnant or breastfeeding? Ask your doctor first.
• Stop at least 2 weeks before surgery due to its blood-thinning effects
• Ask your doctor if you take blood thinner medications like warfarin (coumadin)
• If you take any medications including metformin or insulin, ask your doctor first
• The spice might interact with other blood sugar-lowering supplements like chromium and berberine. This may make your blood sugar go too low.

Cinnamon is sometimes criticized because it contains coumarin, a compound found in many plants. Cassia cinnamon has more than most.  Coumarin is thought to be liver toxic in high doses. Most of the research comes from animal studies but it has been reported in a 73-year-old woman.  There are not many human reports of liver damage from this spice.

That said, the risks of cinnamon vs. type II diabetes and metabolic syndrome are not the same. There are far more health risks of having type II diabetes and metabolic syndrome.

What Do I Suggest?

If you're going to try a supplement, here are the brands and dosages found to help prediabetes and type II diabetes:

• Solgar 1500 mg
• Puritans Pride (1000 mg)
• Cinnulin PF 500 mg

Of those, I'd go with the Solgar brand first.

Suggestions: Pick one and stick with it for a month or so. You'll know by then if it's lowering blood sugar.  It may take at least 3 months to see reductions in A1C levels. Do not take all of these supplements at the same time.

Does Cinnamin Work?

So does it help prediabetes? While several studies have noted cinnamon can lower blood sugar levels,  only a few of them have specifically looked at people with metabolic syndrome (pre-diabetes). I think there is enough research to suggest cinnamon can modestly lower blood sugar levels. That said, if cinnamon pills are going to be an effective treatment for reversing and curing prediabetes, they need to be combined with eating fewer calories, weight loss, and exercise.

What Do You Think?

Glutathione is a very important antioxidant and detoxifying agent that helps rid the body of chemicals such as environmental chemicals to some drugs too (like alcohol and acetaminophen/Tylenol). As we age, we tend to make less glutathione. Some health problems like HIV, liver problems,  cancer, and diabetes also lower your levels. In this review, you'll learn about 6 easy ways to boost your levels. Some of these methods are free too.  How many did you know about? Bonus Tip: in the video watch for what I say about peeling onions too.

How To Raise Glutathione Levels – The Easy Way

In this video, I show you the proof for 6 ways to boost your glutathione levels.

Any Glutathione Side Effects?

If you make it naturally, like from foods or exercise, it's safe. While taking supplements is unlikely to be a problem for most people, here are some things to keep in mind. This list is not complete:

• If you have cancer, ask your doctor first. Same thing if getting chemo or radiation therapy.
• Ask your doctor if your pregnant /breastfeeding
• Supplements are not for children
• Stop taking supplements at least 2 weeks before having surgery
• How it interacts with medications is not well understood

What do you think?