Update 10/18/21. Arthri D (also called Arthri D3) is arthritis and anti-inflammation supplement that you may have seen advertised in a 30 minute TV commercial. After watching the 30-minute infomercial, you may have wondered, does Arthri D work, or is it a scam? Well, one thing is this supplement contains an ingredient ―called N acetyl glucosamine ―that I don't see in many arthritis products. Does that ingredient make it better? It was this ingredient that made me want to review Arthri D3 in case you were wondering the same thing. Let's see if Arthri D is right for you.
What Does Arthri D Refer To?
The letters “arthri”is a reference to arthritis. The “D” in Arthri D3 refers to vitamin D3, the type of vitamin this supplement contains. Hence the reason it's also called “Arthri D3.” There are basically 2 different types of vitamin D:
- Vitamin D3, also called cholecalciferol
- Vitamin D2, also called ergocalciferol
Arthri D gives people 1000 IU of vitamin D3 in two capsules. While that's nice, it's possible that people may already be taking 1000- 2000 IU of vitamin D daily, given all the publicity this vitamin has been getting over the past several years. If not, I suggest getting vitamin D levels checked so you know what your levels actually are.
See the review on Vitamin D Facts.
Arthri D Research
Research conducted specifically on Arthri-D cannot be located. This doesn't not mean it does not work. Rather, it just means we need to look at the proof for its ingredients. Let's do that next.
Arthri D Ingredients
According to the ArthriD.com website, these are the ingredients in 2 capsules.
Vitamin C | 7 mg / 10%DV |
Vitamin D3 | 1000 IU / 250 DV |
Magnesium | 40 mg / 10% DV |
Proprietary blend | 1027 mg |
N-Acetyl-D-Glucosamine (NAG) | |
Chondroitin sulfate | |
Tumeric Extract | |
Rice Flour | |
Boswellia Serrata | |
Ashwaganda | |
Yucca (root) | |
Bromelain | |
Evening Primrose oil | |
Perna Canaliculus (Green Lipped Mussel) | |
Hyaluronic Acid (Sodium Hyaluronate) |
Let's take a closer look at the ingredients in Arthri D and see what the arthritis research says.
Vitamin C
Vitamin C, besides being one of the most famous antioxidant nutrients around the world, also helps us make collagen protein. Collagen is found in joints and is damaged in arthritis. So, it makes sense that it should be in an arthritis supplement. There is not a lot of vitamin C in Arthri-D.
Vitamin D
Vitamin D – which is more like a hormone than a vitamin – does many things. Evidence suggests people with low levels of vitamin D (and that's probably many of us) tend to have more rheumatoid arthritis. Rheumatoid arthritis is different from osteoarthritis, which is the more common type.
Rheumatoid arthritis is often said to be an autoimmune disease. Vitamin D does seem to help make the immune system smarter, so it makes some sense it might help. While vitamin D may help support the immune system, supplements don't seem to improve arthritis pain. The same is true for osteoarthritis pain, too.
Two capsules of Arthri-D provide 1000 IU of vitamin D3. That is a good amount. Vitamin D3 is the version of the vitamin we make when we are exposed to sunlight.
See the vitamin D review for much more information.
N-Acetyl Glucosamine
Also called “NAG.” How much NAG is in Arthri D3? They don't tell us. They only say that the “proprietary blend” contains a total of 1027 mg (about 1 gram). Since NAG is listed first, it makes up most of this blend.
I don't see many arthritis supplements that contain this type of glucosamine. Most products contain either:
- Glucosamine HCL
So, does it work?
A study published in 2001 titled Oral polymeric N-acetyl-D-glucosamine and osteoarthritis. This investigation consisted of 10 people with osteoarthritis. People either received 1.5 grams of N-acetyl Glucosamine (NAG) or a placebo for 6 weeks.
It's important to note that this study did not specifically use N-acetyl glucosamine (NAG) but rather a polymer complex of NAG, called “Poly Nag” produced by a company called Lescarden. This Poly Nag complex consists of both glucosamine and N-acetyl glucosamine.
Researchers noted that those getting the Poly Nag supplement showed improvements in osteoarthritis pain scales compared to the placebo.
This study actually stated there was a “significant improvement” in osteoarthritis pain. But, -unlike most studies – there is no mention of the statistics associated with this effect. Without getting bogged down in math, let me just say that the omission of statistics (like P values) is a big problem with this study.
Researchers in Japan, in 2006 noted a soy-milk beverage containing 1250 mg of NAG reduced arthritis pain in the knees more than just soy milk after 12 weeks of use.
In 2017, researchers in Japan noted that NAG improved cartilage metabolism. This investigation involved healthy people who did not have arthritis and were given 500-1000 mg of NAG per day.
Other than these investigations, most other research located involves involved lab animals or were test-tube studies. Here is a summary of some of those studies:
- Suppressive effects of N-acetyl-D-glucosamine on rheumatoid arthritis mouse models. This is a mouse study.
- Effect of glucosamine, a therapeutic agent for osteoarthritis, on osteoblastic cell differentiation. This is a test tube study.
- Chondroprotective effect of N-acetylglucosamine and hyaluronate in early stages of osteoarthritis–an experimental study in rabbits. This is a rabbit study. NAG was injected into rabbits.
- Chondroprotective activity of N-acetylglucosamine in rabbits with experimental osteoarthritis. This is a rabbit study. NAG was injected into rabbits.
While lab animal research is nice to have, human proof is better.
While NAG does contain glucosamine, I believe there is more evidence for glucosamine sulfate than NAG supplements when it comes to arthritis pain.
Can Potassium Reduce Arthritis Pain?
Watch on my Youtube channel if you prefer
Chondroitin Sulfate
Chondroitin sulfate is popular in arthritis supplements, but it's difficult to say how effective it might be. Some studies have noted that chondroitin sulfate (alone and in combination with glucosamine sulfate) might help osteoarthritis (particularly knee arthritis). For example, this study:
On the flip side, other studies noted chondroitin sulfate does not help arthritis. Some of those studies include:
I'm on the fence when it comes to chondroitin sulfate helping arthritis. I' want to see more research. Men, talk to your urologist if you have prostate problems.
Turmeric
Also known as Curcuma longa and curcumin. This herb has anti-inflammatory effects. Since inflammation often accompanies arthritis, it makes sense that turmeric would be in arthritis supplements. Other supplements containing turmeric that have been reviewed include
One arthritis study located involved a supplement called “Meriva” which contains turmeric and Phosphatidylcholine which is said to boost the absorption of turmeric. On the Meriva website, they call this a “Curcumin Phytosome.” A “phytosome” is a man-made word used to describe something that is better absorbed, in this case, turmeric.
That said, one easy way to boost turmeric absorption is to add some black pepper. I've often added black pepper and turmeric to my smoothies.
Here are Turmeric Supplements on Amazon
Rice Flour
I am not aware of any arthritis research on rice flour.
Boswellia Serrata
Boswellia (also called frankincense) has anti-inflammatory properties. So it makes sense to use it in arthritis supplements. There is also arthritis research on this herb also.
In one investigation, a Boswellia supplement called Aflapin (now called ApresFLEX) improved arthritis pain in 60 people with osteoarthritis after 30 days of use. The dosage used was 100 mg per day. There have been other studies on ApresFlex too showing it may help.
On the flip side, though, researchers in 2008, looking at several other boswellia studies, noted that while boswellia appeared “clinically effective” and “encouraging” for a number of conditions like arthritis, Crohn's disease, asthma, etc., they did not feel the evidence was “compelling.” This lack of endorsement is likely the result of not enough good research on Boswellia.
Ashwagandha
Also called Withania somnifera. Human research suggests this herb may also reduce arthritis pain. Researchers in India, in 2016 noted that 500 mg of ashwagandha given for 12 weeks reduced arthritis pain and joint stiffness more than a placebo.
Other research suggests ashwagandha might help protect cartilage cells. Theoretically, this might help arthritis. Ashwagandha has been an ingredient in several other products I've looked at including:
- 1 Db Goddess – a weight loss supplement
- Mdrive – a “for men over 40” supplement
- Protandim – an anti-aging supplement
See those reviews for more insights
Yucca
Also called Yucca aloifolia. Like several other ingredients in Arthri D, yucca might have some anti-inflammatory properties, but I can't find any conclusive proof it specifically helps arthritis in humans.
Bromelain
Also called Ananas comosus. Bromelain is an enzyme found in pineapples. It's a protein-digesting enzyme, ans also seems to have anti-inflammatory effects. The use of bromelain for arthritis is a bit controversial.
In a 2006 study, bromelain didn't help arthritis pain any more than a placebo did.
In another study from that same year, a specific type of bromelain supplement (Phlogenzym) appeared to help arthritis pain as much as an anti-inflammatory drug. But, this supplement contained more than just bromelain. So, how much of the effect was due to bromelain by-it-self is unknown.
Evening Primrose Oil
Also called GLA, Borage Oil, Oenothera biennis and gamma-linolenic acid. This is an omega 6 fatty acid and like many other ingredients in Arthri-D3, it has anti-inflammation effects.
In a study from the 1990s, researchers noted 2.8 grams of GLA helps rheumatoid arthritis more than placebo after 6 months of use.
Perna Canaliculus
Also called Green Lipped Mussel. This is an extract from a mollusk that seems to have anti-inflammatory properties. Whether or not Perna Canaliculus helps arthritis or not is open to debate. There are studies showing it might help arthritis and other studies noting that it doesn't help arthritis.
See the Omexa XL review. I do a deep dive into the green-lipped mussel /arthritis research there.
Hyaluronic Acid
Also called Glycosaminoglycan. Hyaluronic acid is sometimes found in arthritis supplements however the bulk of the research of it helping arthritis stems from injecting it into joints ―not taking it orally. Whether or not injections of hyaluronic acid help varies from person to person.
But what about hyaluronic supplements? The research is inconsistent. Like injections, it's not known if everybody would be helped by this compound.
Arthri D Ingredients With Evidence
- Chondroitin sulfate
- NAG (maybe)
- Tumeric (maybe)
- Boswellia (maybe)
- Perna Canaliculus (maybe)
Of these 5 ingredients, it's chondroitin sulfate that has most of the evidence that it might help arthritis. The evidence for each of the other 4 ingredients is much weaker. Of course, it's possible all of these might have a better effect on reducing pain than any single ingredient.
Who Is Jim Shriner?
Jim Shriner, is the person I often see on Arthri D3 infomercials. He's a former American Gladiator (I loved that show!) and the author of several books including:
Arthri D3 Anti & Inflammation
From the ingredients, we can suspect one of the ways Arthri D3 is supposed to work is by reducing inflammation.
- Tumeric
- Boswellia
- Ashwagandha
- Yucca
- Bromelain
- Perna Canaliculus
Arthri D: Natural COX 2 Inhibitor?
In an infomercial for this supplement I saw, Jim Shriner (the main spokesperson for Arhri D) says that the ingredients in Arthri D3 contain natural COX 2 inhibitors. COX is short for “cyclo-oxygenase” (sigh-klo-ox-a-gin-ace). This is an enzyme that takes part in many things, including pain and inflammation. Many drugs you have heard of (like aspirin) inhibit the COX enzyme.
So, is Arthri D a natural COX 2 inhibitor? It's possible that some of its ingredients are, but it would take clinical proof to know if Arthri D3 inhibits the COX2 enzyme.
While I think Arthri D3 is safe, talk to your doctor if you take any medications or have health problems.
How Do You Take?
The company recommends taking Arthri D3 with food to minimize any stomach problems. The company states the supplement can be taken with or without food.
Arthri D Side Effects
The supplement is likely very safe in healthy people. I'm not aware of any side effects. Because we are all different, here are some things to consider before using this supplement. This list is not complete:
- Start with less than recommended for the first week or so. If side effects did occur, taking less should reduce them.
- Because N acetyl glucosamine (NAG) comes from shellfish, people who are allergic to shellfish may have allergic reactions. To their credit, the Arthri D website recommends not using the product if you have an allergy to shellfish.
- Glucosamine (and chondroitin) may make asthma worse. This may also be true for N acetyl glucosamine.
- Preliminary evidence hints chondroitin sulfate may increase the risk of prostate cancer. This evidence is not based on human proof. Whether supplements increase the risk is not known. Talk to your urologist if you have prostate problems. I'm sure urologists are aware of this and can guide you properly.
- Talk to your doctor if you take blood thinner medicine. Several of the ingredients in Arthri-D3 have blood-thinning effects.
- Stop taking Arthri-D3 at least two weeks before surgery.
- Avoid if pregnant or breastfeeding until speaking with your doctor.
When in doubt, talk to your doctor and pharmacist.
Who Makes Arthri D?
The website (ArthritD.com) states that Arthri D is distributed by Arthri-D LLC, Beverly, MA 01915.
The company, which has been in business since 2010 is located at 900 Cummings Center Suite 403T Beverly, MA 01915-6184.
Customer service phone number: 800-329-8576.
The Better Business Bureau gives the company an A+ rating.
See the BBB file for updates and more information.
Blue Vase Marketing LLC appears to be the company that either markets Arthri D or produces the infomercial. When this review was updated the BBB gave Blue Vase Marketing a rating of A+.
See the Androzene review for more insights
What Is CloiXonné?
It's possible the bottles you have may contain the name CloiXonné. This is another company that helps produce and distribute Arthri D supplements. They are a direct-to-consumer advertising company. They are also involved with the testosterone supplement Androzene. See that review for more insights.
Contact Arthri-D3
There are 2 contact numbers
- 800-329-8576
- 978-253-0163
Arthri D Recall
In January 2018, the company alerted the FDA they were recalling a specific lot of the supplement (Lot#1701-092 / manufactured March 2017) because it might have been contaminated with Salmonella, a bacteria which can be dangerous especially in those with weak immune systems.
This contamination was noted after routine testing by the company and was only found to occur in 1 bottle. The company promptly halted production and addressed the situation.
Sometimes, recalls like this happen with supplements and even food. It sounds like the quality control is very good, and the company caught this before it got out of hand. This is a good sign that the company is doing a good job ensuring a safe supplement.
Where To Buy Arthri D
This supplement can be purchased directly from ArthriD.com and it may be available on Amazon too. The supplement does not seem to be sold at Target, Walmart, Wegmans, BJs, Costco, GNC, Vitamin Shoppe, Vitamin World, or Sams Club. It can be purchased at its website (ArthriD.com).
Arthri D Price
So how much is Arthri D3? Here is the cost of the supplement listed on the company website (arthrid.com)
- 3 bottles: $229.98 + $9.99 shipping = $239.97
By choosing the 3-bottle option, you are entering into a subscription. This means every 56 day,s the company will send you 1 bottle so you do not run out. The cost of each bottle is $89.99 (+ $9.99) = $99.99.
Previously, the company offered the option to purchase 1 and two bottles at a time. It is not known if this is still available so call ArthriD customer service for more information.
For what it's worth, I think Arthri D3 is expensive.
Arthri D Purchase Policy
The purchase policy page of Arthrid.com states when you buy Arthri D from the product's websites, the credit card used will be charged on the day the product is bought.
If you buy Arthri D from the product's website, you may be enrolled in a “Monthly Replenishment Program.” This means that your credit card will be charged each month as more of the product is shipped to you. Be sure to ask customer service about this if you want to opt out of this program.
Arthri D Return Policy
According to the Arthrid.com purchase policy page, each 30 day supply of Arthri D comes with a 30-day return policy. The 30 days begins on the day the product is received. If you purchase a 90 day supply, you have a 90-day money-back guarantee.
To return Arthri D, follow these steps as is outlined on the ArthriD.com purchase policy page:
1. Call their Customer Satisfaction Department at 800-609-7247. Ask for a Return Authorization Number (RA number). Ask customer service for the address to return the product to. The RA number must be placed outside the package.
2. Include a copy of your original invoice AND provide a reason why you are returning the supplement. Use Fed Ex or UPS to return the package so you have a record that it was sent and received.
3. Return Arthri D within 10 days of getting the RA Number. ALL returned bottles and empty bottles (and refused bottles) will be subject to a $10 restocking fee. So, for example, if you bought 3 bottles, $30 will be deducted from your refund. Note. Refunds are only given to bottles that are returned. It can even be empty bottles.
4. Return shipping and handling costs are non-refundable.
Arthri D vs. The Competition
How Does this supplement compare to other arthritis supplements? Here's a quick rundown:
Arthri D vs. Provailen
Provailen contains different ingredients. Specifically, it contains reishi mushrooms (ganoderma lucidum ) as well as capsicum and Lonjack Tongkat Ali. No studies have compared these supplements to each other to see which might be better.
See the Provalen review.
Arthri D vs. Anatabloc
Anatabloc was once the hottest selling arthritis supplements in America. Because of problems with the FDA and some other entanglements, it is no longer sold in the US.
See the Anatabloc review.
Arthri D vs. Omega XL
Im sure everybody has seen Larry King talking about Omega XL on TV. Omega XL contains green-lipped mussel extracts which some research finds may help arthritis pain. While no study has compared Omega XL to Arthri D, the supplement does contain green-lipped mussel.
See the Omega XL review.
Arthri D vs Omax 3
Omax 3 is a fish oil supplement you may have seen advertised on TV. It contains EPA and DHA (fish oils). There is no EPA or DHA in Arthri D.
See the Omax 3 review.
Arthri D vs. Australian Dream
Australian Dream is an arthritis cream you may have seen game show host Chuck Wollery discussing on TV. Australian Dream contains an interesting ingredient that when applied to the skin may temporarily relieves arthritis pain.
See the Arthritis Dream review.
Arthri D vs. Arthro 7
I often confuse these supplements because their names sound alike. Arthro 7 has a few ingredients in common – like bromelain and turmeric – but it also has other ingredients such as Cetyl myristoleate (CMO) not found in Arthri D. No studies appear to have pitted these supplements to each other.
See the Arthro 7 review.
Arthri D vs. Instaflex
Instaflex is a popular arthritis supplement that is sold at GNC and other health food stores. Instaflex shares several ingredients in common with Arthri D such as turmeric, Boswellia and hyaluronic acid.
See the Instaflex review for more information.
Arthri D vs. Zyflamend
Zyflamend is a very interesting joint supplement that has several clinical studies to support its use. Zyflamend has even been tested to see if it helps cancer too. Most of its ingredients are different than Arthri D.
Read the Zyflamend review for more insights.
Arthri D. vs. Supple
Supple is an arthritis supplement drink that has been around for several years. You may have seen its TV commercial which featured a doctor. Supple contains glucosamine and chondroitin. Supple is not a pill but rather a powder you mix with water or juice. There is also a ready-made supple drink too.
Arthri D vs. Joint Juice
Like Supple, Joint Juice is another liquid glucosamine and chondroitin sulfate supplement. It's widely available online and in stores.
See the Joint Juice review.
Arthti D. vs. Tart Cherry Juice
Tart Cherry Juice got a lot of publicity when it was featured on the Dr. Oz show. Some studies suggest the antioxidants in tart cherries can reduce pain and even help you sleep better. How it stacks up to other arthritis supplements is not known.
See the Tart Cherry Juice Review.
Arthri D. vs. Cissus Quadragularis
Most people have probably not heard of Cissus quadragularis. Its an herbal supplement that can be purchased by itself and it may appear alongside other ingredients too. The herb has been promoted for many reasons including arthritis. There is some research on cissus and some people swear by it. I'd like to see more research.
Arthri D Pro And Con
This review was very big and detailed. To help you put things in perspective, here's a quick review of what I liked and didn't like about this supplement:
Liked | Didn’t Like |
Good quality control | Expensive |
Sensible ingredients | No research on supplement |
Been around a long time | |
Refunds on empty bottles |
These are my opinions. What matters to you may be different.
Does Arthri D Work?
It will take research on Arthri D3 to know if it works. To me, Arthri D looks like an NAG and chondroitin supplement. It does have other ingredients and it's possible those additional ingredients might bolster its effects. While results with the supplement will probably vary according to how bad your arthritis pain is, my guess is if it works, you should feel results in 30-90 days.
Here's Arthri-D on Amazon
Mike says
You can also buy it on Amazon.com. Personally, I buy Flex Protex D — it’s the exact same ingredients, has been around a lot longer, and is much less expensive. And Amazon.com ships to Canada.
Paulette says
Where is the Arthri D manufactured? I live in Canada, can I get it shipped there?
Joe says
Paulette, I provided the address in my review. There is a link at the bottom where you should be able to get it as well.
Kenneth Kelsch says
Very useful and great idea to provide additional details of options. Please do continue this kind of get into details on Arthri-D3. I am using it and find it helpful but not the 4 pills/day as they recommend. Being 53 and 1000s of miles of running I do feel the pain in the knees. I would say without exercise it would only get much worse. Again great work!
Joe says
Thanks Kenneth!
Roseann Turner says
I am forever grateful for someone like yourself who researched this product and gave us the results without any bull..I am a 65 year old woman who avoids doctors at any cost. I take no medication except a pain reliever for my knees..I have tried a few of thee products…not Arthri-D…thanks to you and have found that the more I am up on my legs and walking the better they are.
I suffer with pain but it hasn’t gotten to the point where I would consider a knee replacement. Thank god for people like you who will go that extra mile to protect people like me. God bless you.
Joe says
Roseanne, you are VERY kind and I truly appreciate your words. I’m glad you are doing some exercise to help strengthen your legs and that it is helping reduce your knee pain. Have a wonderful 2016 and let me know if I can be of any other service.
Michelle says
I truly appreciate the thorough research. Thank you for sharing!
Joe says
Michelle, you are most welcome! 🙂
Bella says
As soon as this Jim used the example that if you went to the doctor with a nail in your foot the doctor would leave the nail in and give you pain meds he turned me off. I got the impression he was addressing his comments to morons and perhaps he should because only a moron would believe this dripple
Ms.Connie says
Joe What you heard about Xanjel? Have RA bad now @ 73! Thanks!
Joe says
Ms. Connie, is it a supplement or a prescription medication? I looked for it but could not find it. do you have a website for it?
Terrie Williams says
Was looking for some input on this product because of the cost. This was very informative. I have done a lot of research on herbs, essential oils and every day weeds. The ingredients in this are all anti inflammatory or are for muscle and joint conditions.
I am sure it will work to some extent. Just not sure it will relieve the pain if your cartilage is pretty much gone . With that said I will probably order from Amazon as I am a prime member so shipping is free. Thank you for breaking it down so well.
Joe says
Terrie, thanks for writing and I’m happy my review was of use to you. I hope Arthri D works for you. Let me know what happens when you try it.
Joe says
Thank you for such an in-depth analysis of the product(s). This was the only review of this product (and other products) that I could find which gave me more facts than customer comments. The more comments I look at, the more I am believing that many of them are made up and provided by people working for the companies selling their product. THANK YOU Supplement Geek!
Joe says
Joe, you are very welcome and I thank YOU for the very kind words. I am happy to have been of service to you 🙂
Vince says
that was a really awesome review… Thank you so much I take almost all that stuff already in different stuff I’m taking from purity products I’m also taking a couple brain supplements I wonder if you have a review on prevegin. once again thank you very much
Joe says
Vince you are very welcome. Yes I have reviewed Prevagen. Here is the link:
http://supplementclarity.com/prevagen-review/
Jo Mitchell says
I put my husband on Arthri-d last Sept. 2014. He was in so much pain in knee and Hip, and could barely stand straight when he walked. Within a few weeks I noticed the difference, and in a month I no longer heard his daily complaints about why he could not do anything…the pain is gone, and he walks normally.
My husband has CHF, diabetes, plus only one kidney. My husband’s knees were injured in the 60s because of football, and he had many surgeries. His Dr. told him he needed knee and hip replacement, it never gets brought up anymore. He is 71, and over the years we have tried every product, plus numerous prescriptions. Most of them just masked the pain. I am grateful that his arthritis pain is gone because of Arthri-d. It works!!!
Rita says
My lower spine (L3-S1) discs are almost completely gone (hereditary progressive degeneration), and “full of osteoarthritis”. Plus I have nerve entrapment and damage in my left leg. At 52 years old I had listened to my neurosurgeon and accepted that “there was nothing they could do”.
But, I have been taking Arthri-D3 for 7 weeks, and saw amazing results within 1-2 weeks. I still have “not so good” days, but for the first time in years I now have “great” days – almost fully functional. I can actually walk up stairs one foot in front of the other without short stepping and pulling myself up by the handrail most days now.
As for cost, I called them and said I couldn’t afford the $108/month ( $99 product + S/H), so they reduced my monthly cost to $59 + S/H. Still expensive, but worth it! And even though I am on Hypertension, Diabetic, Respiratory, and other prescription meds, my primary care physician was totally on board with me taking this, and there have been no drug interactions.
Joe says
Rita, very glad to hear Artha D is helping you. Really glad there are no medication issues either and that the company was willing to work with you on the price.
Mike says
Hi Rita,
Great to hear that Arthri-D is working so well for you. If cost is an issue, check out Flex Protex D. The exact same ingredients (Flex Protex has been around a lot longer, since about 2005) but much less money on Amazon and eBay. I usually find Flex Protex D for between $20 and $30 a bottle, or even less for bigger quantities.
Nathan says
I believe many of these posters are affiliated with the sellers of this way overpriced product. Furthermore the placebo effect can be very strong for many people. After all they have to justify being suckered into spending $99 plus for something that’s not even worth $10. Last year I saw a report on the news that after a 10 year study chondroitin was proven to be totally ineffective. America is being scammed!
Joe says
Nathan, anything is possible. For what its worth, while I do tend to take people at their word, I also try to weed out fakers/spammers. While I have not caught any faker posters here, I have on other reviews I’ve written.
aska says
TIM,
I tried and worked. After 1 week of using I noticed significant improvement. It is amazing supplement. Unfortunately, it is too expensive, and I can’t afford it right now. I purchased and used 2 bottles, I was desperate. I was in severe pain, wasn’t able to bend my knees at all, and after just 1 bottle I was able slowly to climb the stairs. IT WORKS.
Matt says
Hi Aska,
It definitely works — I’ve used it myself. But if Arthri D is too expensive for you, try Flex Protex D. Flex Protex D has actually been around longer (since 2005 I believe) and it’s the exact same ingredients. Flex Protex D is much cheaper, and you can get it on Amazon and eBay.
joy says
I take just about Everything in that bottle separately and for a lot less than $80-$90….I’m forever working on my joints and this product is too too pricey….for me…
I take 4-8K D3 daily, magnesium glycinate or citrate not the oxide in that product….oxide is the worst one can take. I take about 1000mg of mag per day of the ones I mention.
Gotta learn to do all this on your own. I take glucosamine sulfate daily, and turmeric and not taking boswella now, but have.
My latest is niacinamide for OA, 500mg a couple times per day. There is a lot of info on the niacinamide online for OA help and for knees in specifics……
Eric says
Joe, thanks for your info/research and ongoing conversations. I’m 51 and each year over the past five I’ve had Euflexxa injected in my knees. along w/800mg ibuprofen and topical Tiger Balm, it relieved knee discomfort enough to play soccer. That is until recent November injections.
Following injections, I’ve had intense knee inflammation (temporarily resolved w/Voltaren topical, ice & ibuprofen). But I’m no longer able to run at even 60% prior performance. I eat lots of veggies & fruits and little to zero red meat. daily take gluco/chondr, Vitmns Omega3,D & multi. This degeneration came on quickly. Anything you can recommend? I almost pulled the trigger on Arthri-D.
Joe says
Eric, have you told your doctor about the knee inflammation? How long has this been going on? Im wondering if maybe this is just temporary irritation due to the injection? As far as I can tell glucosamine sulfate has more evidence but some people have said some good things on
Zyflamend (click to see my review)
As a rule I’m not a fan of chondroitin sulfate for men.
Eric says
Thanks. I’m hoping temporary but it’s been 6 weeks. 4wk follow-up w/Dr resulted in Voltaren gel prescription. Volt’s helped w/pain but stiffness & lack of knee flex continues. perhaps Hot Yoga is a possible solution since moving to a drier climate isn’t an option. Oh well. Thanks for the Zyflamend idea.
joy says
Eric, not Joe, but Joy here….and I’m OLDER, and working to save my knee from any surgery….after 2 rounds of HA injections I never did anymore, they never helped me so I did not go on with them….I had synvisc one year and couple yrs later Eufflexa…nadda…
I take max dose of glusosamine sulfate daily 1500mg, Danish Rose Hips for pain and stiffness, Ligaplex II for chronic ligament/tendon issues….going into my 4th month with this supp. Omega 3’s daily max dose.
I’m trying a bottle of liquid HA and we’ll see how that goes….I’m not into any sports NOW and just wanting to save my knee from any surgery.
Coconut Oil is great for inflammation and I use it daily in cooking and just taking it from the spoon….take a spoon before bed and sleep better and feel it helps too re pain etc….
I take 800mg ibuprofen daily, 400mg before bed and 400mg about 1:30PM or so…and DGL for stomach protection….saves my stomach.
Pain RX supplement is good in between the ibuprofen.
Topricin is my BEST topical.
Prolotherapy is a option and Prolozone (oxygen/ozone) also for saving joints….
And wear a knee support….hip replacement in 2010 was a minor nightmare.
joy says
Eric, jointrehab.com is a good link to check out PRP Prolo and Stem Cell Prolo.
Maybe time too, to be MORE gentle with your joints….
Brittany says
Thank you for your time in researching this! I am beginning to feel the effects of arthritis at 27 y/o in my hands and knees and the doctors are unable to figure it out after extensive blood work, so I’m looking for natural health solutions to reduce the pain. I appreciate your time you spent to put this together, thanks!
Joe says
Brittany, Thanks for the feedback. Im glad I could help. Does anyone in your family have arthritis and got it at such a young age? Have you met with a rheumatologist? If not, that is what I recommend.
Paul Randolph says
I started using Arthri-D about 5 weeks ago and as far as I am concerned it is doing something. I am an avid golfer, 74 years old, and the only reason I started using it was to see if it could help me swing the golf club. I went to a Physical Therapist for about 2 months, twice a week, and did not feel any effect except when I saw how much they charged the insurance company, $900.00 a visit. Yes, insurance paid for it since I was referred by my doctor but I stopped because I felt it was not doing any good and the price I felt was stupid – I could have gotten better results at Gold’s Gym for 5% of that cost.
Back to golf, for the last 2 weeks have have felt much better swinging the club and have even played 36 holes on 1 or 2 days, something I was not able to do a few months ago and my scores have improved also. One round in the 70’s and the rest in the 80’s so far. I do not look at the extensive research that you did as to whether it will help me or not. I just decided to try and am glad I did and have since recommended it to others. If the FDA were to use your method of research when ASPIRIN was coming on the market it would never have been approved.
Paul
Joe says
Paul, Im really glad ArthriD has been helping you. My guess is that it may be the anti-inflammatory ingredients. That said, I stand by my review and the conclusions I reached and your aspirin analogy is way off base. Aspirin has a LOT of research. ArthriD has none.
Todd says
Lol… actually u could only get aspirin with a prescription at the time when you could get laudenum, morphine, heroin, and cocaine over the counter.
joy says
Cough cough cough….$900 a PT visit….I’ve done a lot of PT thru Medicare and my co pay was $10-$15 and Medicare paid about $100 or so per visit as I recall….did a lot before hip replacement to try to “save” myself from the surgery……but I lost….
I know there is a lot of fraud in the insurance world, but $900 a visit, Please…..what did your PT use gold instruments etc…..
I haven’t looked at the ArthriD ingredeitns lately, maybe I need to look at them….. .
Jan says
How do you feel about Heal-n-Soothe?
Joe says
Jan, Ive never heard of Heal-n-soothe but I looked it up. It appears to be an anti-infmattory supplement based on enzymes. Since enzymes are proteins, I’m not sure if they can survive the digestion process. As such I’m not convinced enzyme supplements reduce inflammation. If you try it and it helps, let me know. I noticed the guy who promotes it is Jesse Cannone. He spells his name differently than me (Cannon).
Jan says
I am trying it and see some relief, but am also doing PT so can’t say for sure that one is working better than the other. 🙂
Joe says
Jan, it should take glucosamine 8-12 weeks before it kicks in. I am glad you are doing physical therapy as that can help too. since you started them at the same time basically, it will be hard to say which is working although as long as your pain reduces, I’m a happy camper.
joy says
My integrative MD is always pushing Wobenzyme, it’s pricey, so I’ve found Flavenzyme, almost same ingredients and less pricey….I’ve taken systemic enzymes off and on but back on now….don’t know if Flav is helping, it’s too soon to know…BUT since I’m taking Ligaplex II from Standard Process I “think” I’m helping to save my knee joints…..look at Ligaplex II…it contains a mineral Manganese which MANY of us are deficient in or very very low…..amazon sells Lig and many customer reviews but also SOME chiropractors carry the Standard Process line….I’m on Ligaplex II for just about 2 months now….
I did a mineral test back in 2005 and manganese came up very low….I’m talking manganese and not magnesium, which we need too….deficiency on both these minerals which are needed for bone health.
joy says
I just found a nice natural remedy site: everydayroots.com operated by a woman out of minnesota..she lists 14 natural remedies, some of them I’ve used over the years but trying some new ones now for the OA I deal with. There is a blog attached to this site too.
Joy says
I like higher doses of Celadrin, trying Dr. Best product and read a lot of reviews on iherb from those who take it and in higher dose….
I deal with all over body OA and everything worse since hip replacement, ended up with shorter leg and it’s affected knee and foot/ankle….so much misery for the last almost 4 yrs.
My feet have become a major FOOT ACHE, not headache….
Lysine is good for nerve damage, as is cetyl l carnitine, which I’m trying now, and swansons sells a Nerve Pain homeopathic which I should receive soon.
I ended up with a mess of nerve damage from anterior hip replacement.
As well I deal with too much OA and Fibro issues, pretty minor, in t he whole scheme of everything else that has gone on. I have not taken the Arthri D product…just does NOT “feel right” for me to try….I take a lot of other things though and concentrating on the Celedrin now.
Sharon says
Anybody have ANY?? relief for Mortons Neuroma?? I’ve spent $$$$ on arch supports, only to find out my arches are fine. Just bought a new pair of Super Feet and am breaking them in. I stand for 10-12 hrs. a day and now have MN in both feet – swollen nerve ending between 3 & 4 toes – VERY painful. Purchased a pair of shoes from OESH – shoes for women made by women, but unable to wear cuz my feet hurt too much from work. Have many pairs of yoga slippers which are fab, but can’t wear to work…..I want to heal the neuromas from the inside. Am taking L-lysine for nerve ending repair, but am looking for a final fix. Anybody??
Joyce says
Gay, yes Prolo can work after replacements, sorry to hear about your issues, I have a nasty knee but will do all before I do a surgery again, that hip was enough for a couple lifetimes.
For more advanced issues, PRP (platlet rich plasma) is used and Stem Cells, very advanced. Dr. Darrow here in LA talks about working on SO MANY who had replacements…..
If money is no issue, give this serious consideration. I keep working on my knee with acupuncture, but if I get to a point where I can’t manage it, I’ll check into PRP for my advanced OA knee, no knee surgery for me.
Have you checked into leg length from surgery, SO OFTEN we’re left with leg discrepancy and I now use a 3/4″ heel lift in my operated side shoe.
Gay Schimmoller says
Joyce, keep on with your acupuncture, knee brace and supplements, or anything else for your knee before you have a replacement surgery. The knee has been a much longer and more difficult recovery.
The hip was rotated on reattachment just enough so that my gait is off, as well as my suspicion that the size of the appliance was too large for my stature, thus negating the good effects of both surgeries. I have a hip replacement on the other side that has been satisfactory for twenty years, so didn’t consider the very real possibility of an unsatisfactory result this time.
Many thanks for your reply.
Joyce says
Here is good info on Oxytocin and also DHEA levels which are very OFTEN very low in FM people…I’ve been on top of DHEA for over 10 yrs…
http://www.newswithviews.com/Howenstine/james186.htm